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Segmentation genes of Drosophila embryo [1]. A segmentation gene is a gene involved in the early developmental stages of pattern formation. It regulates how cells are organized and defines repeated units in the embryo.
Multipartite is a class of virus that have segmented nucleic acid genomes, with each segment of the genome enclosed in a separate viral particle. Only a few ssDNA viruses have multipartite genomes, but a many more RNA viruses have multipartite genomes. [1]
Bunyaviruses have segmented genomes, making them capable of rapid reassortment and increasing the risk of outbreak. [ 17 ] [ 18 ] The bunyavirus that causes severe fever with thrombocytopenia syndrome can undergo recombination both by reassortment of genome segments and by intragenic homologous recombination .
A/H5N1 virus can also infect mammals (including humans) that have been exposed to infected birds; in these cases, symptoms are frequently severe or fatal. All subtypes of the influenza A virus share the same genetic structure and are potentially able to exchange genetic material by means of reassortment [ 2 ] [ 3 ]
The segmented genome of influenza viruses facilitates genetic reassortment. This can occur if a host is infected simultaneously with two different strains of influenza virus; then it is possible for the viruses to interchange genetic material as they reproduce in the host cells. [ 37 ]
IAV is an enveloped negative-sense RNA virus, with a segmented genome. [4] Through a combination of mutation and genetic reassortment the virus can evolve to acquire new characteristics, enabling it to evade host immunity and occasionally to jump from one species of host to another.
Many taxa (for example the molluscs) have some form of serial repetition in their units but are not conventionally thought of as segmented. Segmented animals are those considered to have organs that were repeated, or to have a body composed of self-similar units, but usually it is the parts of an organism that are referred to as being segmented ...
Like all subtypes it is an enveloped negative-sense RNA virus, with a segmented genome. [16] Influenza viruses have a relatively high mutation rate that is characteristic of RNA viruses. [17] The segmentation of its genome facilitates genetic recombination by reassortment in hosts infected with two different strains of influenza viruses at the ...