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In clinical practice, this means that it takes 4 to 5 times the half-life for a drug's serum concentration to reach steady state after regular dosing is started, stopped, or the dose changed. So, for example, digoxin has a half-life (or t 1 / 2 ) of 24–36 h; this means that a change in the dose will take the best part of a week to ...
Their new text was first published in 1941 under the title The Pharmacological Basis of Therapeutics: A Textbook of Pharmacology, Toxicology and Therapeutics for Physicians and Medical Student. [1] Because the volume was twice as long as a typical textbook, Macmillan printed few copies, but demand for a readable, up-to-date pharmacological text ...
Clinical pharmacology is "that discipline that teaches, does research, frames policy, gives information and advice about the actions and proper uses of medicines in humans and implements that knowledge in clinical practice". [1] [2] Clinical pharmacology is inherently a translational discipline underpinned by the basic science of pharmacology ...
The Journal of Pharmacology and Experimental Therapeutics (a.k.a. JPET) is a peer-reviewed scientific journal covering pharmacology. It has been published since 1909 by the American Society for Pharmacology and Experimental Therapeutics (ASPET).
Alexander Paffendorf expressed regret for his involvement when a judge offered a chance for final words before keeping an order to confiscate his guns and ammunition in place until April 4.
Montana Republicans in 2023 voted to silence Zephyr from floor debates for breaking decorum after she said lawmakers who backed a ban on gender-affirming healthcare for minors would have "blood on ...
The 2024 Heisman Trophy presentation is less than two weeks away and will feature the top college football players who have demonstrated exceptional skill, leadership and performance on the field ...
According to the Journal Citation Reports, the journal has a 2022 impact factor of 3.4 and a 5-year impact factor of 3.8, ranking it 125th out of 278 journals in the category Pharmacology & Pharmacy. [1] It is in the first quartile of journals in the category "Medicine – Pharmacology (medical)" (51/255).
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