Search results
Results from the WOW.Com Content Network
CR includes a heightened pain sensitivity, and decreased body temperature, and might cause discomfort, thus motivating the drug user to continue usage of the drug. This is one of several ways classical conditioning might be a factor in drug addiction and dependence. [2] In a classic experiment, Shepard Siegel conditioned rats with morphine ...
Cue reactivity is most often conceptualized through models of classical conditioning, such that it is theorized that cues that are nearly exclusively encountered at the time of drug administration will develop the ability to predict the administration and effect of the substance. [8]
When substituted amphetamines are used, drug tolerance develops rapidly. [8] Amphetamine dependence has shown to have the highest remission rate compared to cannabis, cocaine, and opioids. [9] Severe withdrawal associated with dependence from recreational substituted amphetamine use can be difficult for a user to cope with.
Classical conditioning occurs when a conditioned stimulus (CS) is paired with an unconditioned stimulus (US). Usually, the conditioned stimulus is a neutral stimulus (e.g., the sound of a tuning fork), the unconditioned stimulus is biologically potent (e.g., the taste of food) and the unconditioned response (UR) to the unconditioned stimulus is an unlearned reflex response (e.g., salivation).
Contact high is a phenomenon that occurs in otherwise sober people who experience a drug-like effect just by coming into contact with someone who is under the influence of a psychoactive drug. In a similar way to the placebo effect, a contact high may be caused by classical conditioning as well as by the physical and social setting. [8] [9]
Drug addiction has been shown to work in phenomenological, conditioning (operant and classical), cognitive models, and the cue reactivity model. However, no one model completely illustrates substance abuse. [36] Risk factors for addiction include: Aggressive behavior (particularly in childhood) Availability of substance [34]
Heroin addicts who relapse are more likely to fatally overdose than other drug users, but Hazelden hadn’t integrated that fact into its curriculum. Seppala thought that if he was going to reach these addicts and keep them from relapsing, Hazelden needed to revamp its curriculum and start prescribing buprenorphine and other medications.
Drug dosing in self-administration studies is response-dependent. This is an important element of creating a disease model of drug addiction in humans because response-independent drug administration is associated with increased toxicity and different neurobiological, neurochemical, and behavioral effects. [5]