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Reduced affect display, sometimes referred to as emotional blunting or emotional numbing, is a condition of reduced emotional reactivity in an individual. It manifests as a failure to express feelings either verbally or nonverbally, especially when talking about issues that would normally be expected to engage emotions.
Side effects vary depending on the type of medication used. Some common side effects of bipolar medications include weight gain and fatigue or drowsiness. These side effects can usually be managed ...
It can cause a visible slowing of physical and emotional reactions, including speech and affect. [1] Psychomotor retardation is most commonly seen in people with major depression and in the depressed phase of bipolar disorder; [2] it is also associated with the adverse effects of certain drugs, such as benzodiazepines. [3]
The primary treatment for bipolar disorder consists of medications called mood stabilizers, which are used to prevent or control episodes of mania or depression. Medications from several classes have mood stabilizing activity. Many individuals may require a combination of medication to achieve full remission of symptoms. [2]
Bipolar disorder is among the top 20 causes of disability worldwide and leads to substantial costs for society. [23] Due to lifestyle choices and the side effects of medications, the risk of death from natural causes such as coronary heart disease in people with bipolar disorder is twice that of the general population. [4]
People with bipolar disorder often fluctuate between manic periods, where they feel intensely energetic, and depression. Treatment usually includes medications and talk therapy. The exact cause ...
The drug seems ineffective in the treatment of current rapid-cycling, acute mania, or acute depression in bipolar disorder. [25] Lamotrigine has been shown to be as effective as lithium, the standard treatment for bipolar disorder. [26] Lamotrigine has not demonstrated clear efficacy in treating acute mood episodes, either mania or depression.
The most prevalent side effects for endoxifen include headache, vomiting, insomnia. Other side effects were: gastritis, epigastric discomfort, diarrhea, restlessness, somnolence, etc. [8] Some of the adverse events reported with other therapies for the management of manic episodes of bipolar I disorder were not observed during the clinical development program of endoxifen like reduction in ...
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