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A recent study on 38 children concluded that surgery for infantile esotropia is most likely to result in measureable stereopsis if patient age at alignment is not more than 16 months. [24] Another study found that for children with infantile esotropia early surgery decreases the risk of dissociated vertical deviation developing after surgery. [25]
There are three distinguishable forms of this condition: primary constant, primary decompensating and consecutive MFS. It is believed that primary MFS is a result of a primary sensorial defect, predisposing to anomalous retinal correspondence. [4] Secondary MFS is a frequent outcome of surgical treatment of congenital esotropia. [2]
Esotropia (from Greek eso 'inward' and trope 'a turning' [1]) is a form of strabismus in which one or both eyes turn inward. The condition can be constantly present, or occur intermittently, and can give the affected individual a "cross-eyed" appearance. [ 2 ]
Dissociated vertical deviation (DVD) is an eye condition which occurs in association with a squint, typically infantile esotropia. The exact cause is unknown, although it is logical to assume it is from faulty innervation of eye muscles.
Some consider botulinum injections to be a treatment option for children with small- to moderate-angle infantile esotropia. [7] [8] Studies have provided indications that performing injections into both medial rectus muscles may be more effective than an injection into one medial rectus muscle alone. [2]
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The earliest successful strabismus surgery intervention is known to have been performed on 26 October 1839 by Johann Friedrich Dieffenbach on a 7-year-old esotropic child; a few earlier attempts had been performed in 1818 by William Gibson of Baltimore, a general surgeon and professor at the University of Maryland. [2]