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The Disabled-1 (Dab1) gene encodes a key regulator of Reelin signaling. Reelin is a large glycoprotein secreted by neurons of the developing brain, particularly Cajal-Retzius cells . DAB1 functions downstream of Reln in a signaling pathway that controls cell positioning in the developing brain and during adult neurogenesis .
DAB2 mRNA is expressed in normal ovarian epithelial cells but is down-regulated or absent from ovarian carcinoma cell lines. The 770-amino acid predicted protein has an overall 83% identity with the mouse p96 protein, a putative mitogen-responsive phosphoprotein; homology is strongest in the amino-terminal end of the protein in a region corresponding to the phosphotyrosine interaction domain.
Jennifer Kaye Ringley (born August 10, 1976) [1] is an Internet personality and former lifecaster. She is widely regarded as the first camgirl. She is known for creating the popular website JenniCam. [2] [3] Previously, live webcams transmitted static shots from cameras aimed through windows or at coffee pots. [4]
Chaturbate Chaturbate logo Type of site Adult website, live streaming, webcam Available in Multilingual (15) Founded 2011 ; 14 years ago (2011) Headquarters Irvine, California, U.S. Area served Worldwide, except blocking countries Owner Multi Media LLC Industry Pornographic camming Advertising Yes Registration Optional Launched February 26, 2011 ; 13 years ago (2011-02-26) Current status ...
The discount chain said it agreed to a sale transaction with an investment firm which would allow hundreds of stores to stay open by transferring its property to other retailers and companies.
Ex-NYPD Commissioner Bill Bratton says the city needs more cops to crack down on subway mayhem and other crime, noting there were thousands more officers when he was first in charge in the 1990s.
WINNIE, Texas – A weekend fishing trip quickly turned into a quick reversal of circumstances after two anglers hoping for a good catch ended up caught in a strong tornado.. That tornado was part ...
The XBIZ Award for Live Cam Site of the Year was awarded to MFC in 2011, 2012, and 2013. [19] It was additionally named one of the top 50 Industry Newsmakers of 2011 by XBIZ. [20] In 2014, MyFreeCams.com won an AVN award for Best Live Chat Website. [21]