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Clomipramine, sold under the brand name Anafranil among others, is a tricyclic antidepressant (TCA). [7] It is used in the treatment of various conditions, most notably obsessive–compulsive disorder but also many other disorders, including hyperacusis, panic disorder, major depressive disorder, trichotillomania, [8] body dysmorphic disorder [9] [10] [11] and chronic pain. [7]
For depression, the starting dose for fluoxetine is usually 20 milligrams per day. Research shows it typically takes four to six weeks to fully feel its impact. Research shows it typically takes ...
Children ≥6 years α 2 adrenoceptor agonist: Approved: Delayed onset of action (1 week). Insufficient data to judge its relative efficacy. Only the more sedating, immediate-release formulations are available in some countries, including Australia. [143] Guanfacine: Intuniv, Tenex [144] Children 6 to 17 years Children ≥6 years Children ≥6 ...
In addition to their reuptake inhibition, many TCAs also have high affinity as antagonists at the 5-HT 1, 5-HT 2 [36] (5-HT 2A [37] and 5-HT 2C [37]), 5-HT 6, [38] 5-HT 7, [39] α 1-adrenergic, [36] and NMDA receptors, [40] and as agonists at the sigma receptors [41] (σ 1 [41] and σ 2 [42]), some of which may contribute to their therapeutic ...
December 19, 2024 at 7:06 PM At least 35 children were killed and six others critically injured in a crowd crush at a funfair in southwest Nigeria on Wednesday, police said.
The tricyclic anti-depressant clomipramine (brand name Anafranil) has been anecdotally useful for many people with hyperacusis. Both loudness hyperacusis and noxacusis have been successfully treated with this drug. A dosage of up to 200–250 mg daily for a sustained period of six to twelve months may be needed to cure hyperacusis.
The two kindergarten students who were wounded in a school shooting in the Northern California community of Palermo remain in critical condition after a successful surgery on Friday, the Butte ...
Norclomipramine, also known as N-desmethylclomipramine and chlordesipramine, is the major active metabolite of the tricyclic antidepressant (TCA) clomipramine (Anafranil). [ 1 ] References