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12156 Ensembl ENSG00000125845 ENSMUSG00000027358 UniProt P12643 P21274 RefSeq (mRNA) NM_001200 NM_007553 RefSeq (protein) NP_001191 NP_031579 Location (UCSC) Chr 20: 6.77 – 6.78 Mb Chr 2: 133.39 – 133.4 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Bone morphogenetic protein 2 or BMP-2 belongs to the TGF-β superfamily of proteins. Function BMP-2 like other bone morphogenetic ...
Recombinant BMP-2 and BMP-7 are currently approved for human use. [6] rhBMPs are used in oral surgeries. [7] [8] [9] BMP-7 has also recently found use in the treatment of chronic kidney disease (CKD). BMP-7 has been shown in murine animal models to reverse the loss of glomeruli due to sclerosis.
Type 1 contains a glycine-serine-rich domain to be phosphorylated by type 2 kinase domain, initiating the signaling transduction pathway of the SMAD signaling cascade. [3] The wrist epitope motif on BMP-2 has a high-affinity binding site for BMPR-IA. The knuckle epitope motif on BMP-2 has a low-affinity binding site for BMPR-II. [4]
12168 Ensembl ENSG00000204217 ENSMUSG00000067336 UniProt Q13873 O35607 RefSeq (mRNA) NM_001204 NM_033346 NM_007561 RefSeq (protein) NP_001195 NP_031587 Location (UCSC) Chr 2: 202.38 – 202.57 Mb Chr 1: 59.8 – 59.92 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Bone morphogenetic protein receptor type II or BMPR2 is a serine/threonine receptor kinase encoded by the BMPR2 gene. It ...
BMP2 or BMP-2 may refer to: Bone morphogenetic protein 2; Boyevaya Mashina Pekhoty , a Soviet infantry fighting vehicle; See also. BMP (disambiguation) BMP1 ...
That said, a BMP-2’s autocannon could still defeat a Bradley’s side or rear armor. Bradley from B Company of the 12th Cavalry Regiment launches a TOW missile at the Grafenwoehr training range ...
140780 Ensembl ENSG00000138756 ENSMUSG00000034663 UniProt Q9NSY1 Q91Z96 RefSeq (mRNA) NM_017593 NM_198892 NM_080708 RefSeq (protein) NP_060063 NP_942595 NP_542439 Location (UCSC) Chr 4: 78.78 – 78.92 Mb Chr 5: 97.15 – 97.24 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse BMP-2-inducible protein kinase is an enzyme in humans encoded by the BMP2K gene. Function This gene is the ...
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