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12156 Ensembl ENSG00000125845 ENSMUSG00000027358 UniProt P12643 P21274 RefSeq (mRNA) NM_001200 NM_007553 RefSeq (protein) NP_001191 NP_031579 Location (UCSC) Chr 20: 6.77 – 6.78 Mb Chr 2: 133.39 – 133.4 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Bone morphogenetic protein 2 or BMP-2 belongs to the TGF-β superfamily of proteins. Function BMP-2 like other bone morphogenetic ...
Recombinant BMP-2 and BMP-7 are currently approved for human use. [6] rhBMPs are used in oral surgeries. [7] [8] [9] BMP-7 has also recently found use in the treatment of chronic kidney disease (CKD). BMP-7 has been shown in murine animal models to reverse the loss of glomeruli due to sclerosis.
14560 Ensembl ENSG00000266524 ENSMUSG00000021943 UniProt P55107 P97737 RefSeq (mRNA) NM_004962 NM_145741 RefSeq (protein) NP_004953 NP_665684 Location (UCSC) Chr 10: 47.3 – 47.31 Mb Chr 14: 33.65 – 33.66 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Growth differentiation factor 10 (GDF10) also known as bone morphogenetic protein 3B (BMP-3B) is a protein that in humans is ...
Type 1 contains a glycine-serine-rich domain to be phosphorylated by type 2 kinase domain, initiating the signaling transduction pathway of the SMAD signaling cascade. [3] The wrist epitope motif on BMP-2 has a high-affinity binding site for BMPR-IA. The knuckle epitope motif on BMP-2 has a low-affinity binding site for BMPR-II. [4]
Sclerostin is a protein that in humans is encoded by the SOST gene. [5] It is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists.
The brain cells secrete FGF-8, Wnt5a and BMP-4, and the oral cavity BMP-2. Together, these cellular signals stimulate a group of cells from the oral cavity to form Rathke's pouch , which becomes independent of the nasal cavity and develops into the anterior pituitary; this process includes the suppression of production of a protein called Sonic ...
These 2-Ingredient High-Protein Bagels Are Going Viral, but We’ve Been Making Them for Years. Danielle DeAngelis. December 13, 2024 at 2:55 PM. Reviewed by Dietitian Emily Lachtrupp, M.S., RD.
BMP2 or BMP-2 may refer to: Bone morphogenetic protein 2; Boyevaya Mashina Pekhoty , a Soviet infantry fighting vehicle; ... BMP2K, BMP-2-inducible protein kinase
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