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The basic cause of sporadic (non-familial) cancers is DNA damage and genomic instability. [1] [2] A minority of cancers are due to inherited genetic mutations. [3] Most cancers are related to environmental, lifestyle, or behavioral exposures. [4] Cancer is generally not contagious in humans, though it can be caused by oncoviruses and cancer ...
Tobacco smoke, for example, causes 90% of lung cancer. [50] Tobacco use can cause cancer throughout the body including in the mouth and throat, larynx, esophagus, stomach, bladder, kidney, cervix, colon/rectum, liver and pancreas. [51] [52] Tobacco smoke contains over fifty known carcinogens, including nitrosamines and polycyclic aromatic ...
The central role of DNA damage and epigenetic defects in DNA repair genes in carcinogenesis. DNA damage is considered to be the primary cause of cancer. [17] More than 60,000 new naturally-occurring instances of DNA damage arise, on average, per human cell, per day, due to endogenous cellular processes (see article DNA damage (naturally occurring)).
Scientist Otto Warburg, whose research activities led to the formulation of the Warburg hypothesis for explaining the root cause of cancer.. The Warburg hypothesis (/ ˈ v ɑːr b ʊər ɡ /, [ˈvaːɐ̯bʊʁk]), sometimes known as the Warburg theory of cancer, postulates that the driver of carcinogenesis (cancer formation) is insufficient cellular respiration caused by insult (damage) to ...
Aflatoxin B 1, a toxin produced by the fungus Aspergillus flavus which is a common contaminant of stored grains and nuts is a known cause of hepatocellular cancer. The bacteria H. Pylori is known to cause stomach cancer and MALT lymphoma. [24] Hepatitis B and C are associated with the development of hepatocellular cancer.
This is the only member of this group of viruses known to cause human cancer but other polyomaviruses are suspects for being additional cancer viruses. [citation needed] HIV does not directly cause cancer, but it is associated with a number of malignancies, especially Kaposi's sarcoma, non-Hodgkin's lymphoma, anal cancer and cervical cancer.
Chances are you or someone you know has been affected by one of the many types of cancer.According to the Centers for Disease Control and Prevention, it is the second leading cause of death for ...
Some cancer treatments may further increase this risk. [11] Effusions: Cancers may stimulate fluid shifts in the body and lead to extracellular collections of fluid. Breast and lung cancer, for example, often cause pleural effusions, or a buildup of fluid in the lining of the lungs.
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