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Pethidine is the most widely used opioid in labour and delivery. [16] It has fallen out of favour in some countries, such as the United States, in favour of other opioids, due to its potential drug interactions, especially with serotonergics, and its neurotoxic metabolite, norpethidine . [ 10 ]
The Passaic Agricultural Chemical Works in Newark, New Jersey, 1876. An agrochemical or agrichemical, a contraction of agricultural chemical, is a chemical product used in industrial agriculture. Agrichemical typically refers to biocides (pesticides including insecticides, herbicides, fungicides and nematicides) alongside synthetic fertilizers.
Herbicides are designed and used to control unwanted plants such as agricultural weeds. However, the use of herbicides can cause phytotoxic effects on non-targeted plants through wind-blown spray drift or from the use of herbicide-contaminated material (such as straw or manure) being applied to the soil. [ 5 ]
Pethidinic acid (meperidinic acid, pethidine intermediate C) is a 4-phenyl piperidine derivative that is both a metabolite of and a precursor to pethidine (meperidine). [2] [3] It is scheduled by UN Single Convention on Narcotic Drugs. It is a Schedule II Narcotic controlled substance in the United States and has an ACSCN of 9234.
Hydroxypethidine (Bemidone) is an opioid analgesic that is an analogue of the more commonly used pethidine (meperidine). Hydroxypethidine is slightly more potent than meperidine as an analgesic, 1.5x meperidine in potency, [2] and it also has NMDA antagonist properties like its close relative ketobemidone.
These industries make effective use of local raw materials which also promotes primary industries like agriculture and mining. Small-scale industry does not require much capital and high technology. I.T is suited to the traditional economic set-up. Cottage and small-scale industries do not use much imported material or equipment.
Piminodine (Alvodine) is an opioid analgesic that is an analogue of pethidine (meperidine). [2] It was used in medicine briefly during the 1960s and 70s, but has largely fallen out of clinical use. It was used particularly for obstetric analgesia and in dental procedures and, like pethidine, could be combined with hydroxyzine to intensify the ...
Norpethidine (normeperidine, pethidine intermediate B) is a 4-phenylpiperidine derivative that is both a precursor to, and the toxic metabolite of, pethidine (meperidine). It is scheduled by UN Single Convention on Narcotic Drugs. It is a Schedule II Narcotic controlled substance in the United States and has an ACSCN of 9233.