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An ovarian follicle is a roughly spheroid cellular aggregation set found in the ovaries.It secretes hormones that influence stages of the menstrual cycle.In humans, women have approximately 200,000 to 300,000 follicles at the time of puberty, [1] [2] each with the potential to release an egg cell (ovum) at ovulation for fertilization. [3]
If the egg fails to release from the follicle in the ovary an ovarian cyst may form. Small ovarian cysts are common in healthy women. Small ovarian cysts are common in healthy women. Some women have more follicles than usual ( polycystic ovary syndrome ), which inhibits the follicles to grow normally and this will cause cycle irregularities.
Ovarian follicle dominance is the process where one or more follicles are selected per cycle to ovulate.. In female mammals, each ovulatory cycle, or menstrual cycle in humans, a set number of ovarian follicles ovulate, each follicle releasing an egg that can be fertilised.
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The mature egg has a diameter of about 0.1 mm (0.0039 in), [29] and is the largest human cell. [30] Which of the two ovaries – left or right – ovulates appears random; [31] no left and right coordinating process is known. [32] Occasionally both ovaries release an egg; if both eggs are fertilized, the result is fraternal twins. [33]
The ovarian follicles rupture and release the secondary oocyte ovarian cells. [1] After ovulation, during the luteal phase, the egg will be available to be fertilized by sperm. If it is not, it will break down in less than a day. Meanwhile, the uterine lining (endometrium) continues to thicken to be able to receive a fertilized egg.
The primary role of the follicle is oocyte support. From the whole pool of follicles a woman is born with, only 0.1% of them will rise ovulation, whereas 99.9% will break down (in a process called follicular atresia).
The ovary is generally thought of as an egg bank from which the woman draws during her reproductive life. The human ovary contains a population of primordial follicles.At 18–22 weeks post-conception, the female ovary contains its peak number of follicles (about 300,000 in the average case, but individual peak populations range from 35,000 to 2.5 million [3]).