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Lupus erythematosus is a collection of autoimmune diseases in which the human immune system becomes hyperactive and attacks healthy tissues. [1] Symptoms of these diseases can affect many different body systems, including joints , skin , kidneys , blood cells , heart , and lungs .
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Lupus, formally called systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. [1] Symptoms vary among people and may be mild to severe. [ 1 ]
Lupus can also affect the serosa, which is like the outer membrane of an organ or tissue, so if it gets inflamed, people get get serositis, which could manifest as something like pleuritis, which is inflammation of the lining around the lungs and chest cavity, or as pericarditis, inflammation of the lining of the heart.
Lupus nephritis is an inflammation of the kidneys caused by systemic lupus erythematosus (SLE) and childhood-onset systemic lupus erythematosus which is a more severe form of SLE that develops in children up to 18 years old; both are autoimmune diseases. [3] [4] It is a type of glomerulonephritis in which the glomeruli become inflamed.
Lupus Canada is a national voluntary organization dedicated to improving the lives of people living with systemic lupus erythematosus (SLE) through advocacy, education, public awareness, support and research. Formed in 1987, Lupus Canada is a federally registered non-profit charity and its national office is located in Markham, Ontario.
Kaplan's research has focused on identifying mechanisms of immune dysregulation, organ damage, and premature vascular disease in systemic autoimmunity. [1] She investigates how innate immunity (in particular, type I interferons and myeloid cells) promote autoimmune responses and end-organ damage in systemic lupus erythematosus, rheumatoid ...
Lupus headache is a proposed, specific headache disorder in patients with systemic lupus erythematosus (SLE). [ 1 ] [ 2 ] Research shows that headache is a symptom commonly described by SLE patients —57% in one meta-analysis, ranging in different studies from 33% to 78%; [ 3 ] of which migraine 31.7% and tension-type headache 23.5%.
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