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  2. Atorvastatin - Wikipedia

    en.wikipedia.org/wiki/Atorvastatin

    In a Cochrane systematic review the dose-related magnitude of atorvastatin on blood lipids was determined. Over the dose range of 10 to 80 mg/day total cholesterol was reduced by 27.0% to 37.9%, LDL cholesterol by 37.1% to 51.7% and triglycerides by 18.0% to 28.3%. [103]

  3. Statin - Wikipedia

    en.wikipedia.org/wiki/Statin

    On average, statins can lower LDL cholesterol by 1.8 mmol/L (70 mg/dL), which translates into an estimated 60% decrease in the number of cardiac events (heart attack, sudden cardiac death) and a 17% reduced risk of stroke after long-term treatment. [37] A greater benefit is observed with high-intensity statin therapy. [38]

  4. Older adults over age 70 should consider taking statins ...

    www.aol.com/older-adults-over-age-70-151519096.html

    Overall, our findings suggest that more people over 70 years of age should be considered for statin treatment.” — Borislava Mihaylova, DPhil “Cardiovascular disease remains a leading cause ...

  5. Rosuvastatin - Wikipedia

    en.wikipedia.org/wiki/Rosuvastatin

    The dose-related magnitude of rosuvastatin on blood lipids was determined in a Cochrane systematic review in 2014. Over the dose range of 1 to 80 mg/day strong linear dose‐related effects were found; total cholesterol was reduced by 22.1% to 44.8%, LDL cholesterol by 31.2% to 61.2%, non-HDL cholesterol by 28.9% to 56.7% and triglycerides by ...

  6. Defined daily dose - Wikipedia

    en.wikipedia.org/wiki/Defined_Daily_Dose

    The average cost per DDD of rosuvastatin was 21% more expensive than atorvastatin ($1.14 compared to $0.94), which would suggest the shift at the time from prescribing atorvastatin to prescribing rosuvastatin would result in increased costs to the healthcare budget. Both had a DDD at that time of 10mg, but 10mg was not the only dose prescribed.

  7. Ezetimibe/atorvastatin - Wikipedia

    en.wikipedia.org/wiki/Ezetimibe/atorvastatin

    Ezetimibe/atorvastatin (trade names Liptruzet, Atozet) is a cholesterol lowering combination drug. In the United States, it was approved in May 2013, by the Food and Drug Administration for the treatment of elevated low-density lipoprotein (LDL) in patients with primary or mixed hyperlipidemia as adjunctive therapy to diet. [ 1 ]

  8. Cholesterol - Wikipedia

    en.wikipedia.org/wiki/Cholesterol

    [104] [105] For men ages 45 to 65 and women ages 55 to 65, a cholesterol test should occur every 1–2 years, and for seniors over age 65, an annual test should be performed. [ 104 ] A blood sample after 12-hours of fasting is taken by a healthcare professional from an arm vein to measure a lipid profile for a) total cholesterol, b) HDL ...

  9. Therapeutic index - Wikipedia

    en.wikipedia.org/wiki/Therapeutic_index

    the dose at which toxicity occurs in 50% of cases. LD Lethal Dose the dose at which death occurs in 50% of cases. [6]: 73 [7] [8] TI Therapeutic Index a quantitative measurement of the relative safety of a drug by comparison of the amount of a therapeutic agent that causes toxicity to the amount that causes the therapeutic effect [1]

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