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  2. Plecanatide - Wikipedia

    en.wikipedia.org/wiki/Plecanatide

    Plecanatide, sold under the brand name Trulance, is a medication for the treatment of chronic idiopathic constipation (CIC) [4] and irritable bowel syndrome with constipation. [5] It is available in India under the brand name Plectide (OQM Div, MSN Laboratories, India). Plecanatide is an agonist of guanylate cyclase-C.

  3. Prucalopride - Wikipedia

    en.wikipedia.org/wiki/Prucalopride

    Prucalopride is contraindicated where there is hypersensitivity to the active substance or to any of the excipients, renal impairment requiring dialysis, intestinal perforation or obstruction due to structural or functional disorder of the gut wall, obstructive ileus, severe inflammatory conditions of the intestinal tract, such as Crohn's disease, and ulcerative colitis and toxic megacolon ...

  4. Prokinetic agent - Wikipedia

    en.wikipedia.org/wiki/Prokinetic_agent

    As such, the relatively poor selectivity profile of cisapride versus other receptors (especially hERG [human ether-a-go-go K +] channels) contributes to its potential to cause cardiac arrhythmias. Prucalopride , a first in class benzofuran , is a selective, high affinity serotonin (5-HT 4 ) receptor agonist that stimulates colonic mass ...

  5. Magnesium Supplements Can Help With Constipation, But Make ...

    www.aol.com/lifestyle/magnesium-supplements-help...

    Magnesium for constipation is a doctor-approved treatment. Experts recommend magnesium citrate or magnesium oxide, and say the oral route is most effective. Magnesium Supplements Can Help With ...

  6. What Causes Constipation? 8 Reasons Why You Can't Poop ... - AOL

    www.aol.com/lifestyle/causes-constipation-8...

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  7. Constipation - Wikipedia

    en.wikipedia.org/wiki/Constipation

    Constipation is a bowel dysfunction that makes bowel movements infrequent or hard to pass. [2] The stool is often hard and dry. [4] Other symptoms may include abdominal pain, bloating, and feeling as if one has not completely passed the bowel movement. [3]

  8. But constipation can be complicated. "It's multi-factorial — there are usually several things going on," Dr. Corey Baker , a pediatric gastroenterologist at Connecticut Children's hospital ...

  9. Neurogenic bowel dysfunction - Wikipedia

    en.wikipedia.org/wiki/Neurogenic_bowel_dysfunction

    This neurological problem can also result in reduced sensation of rectal filling and weakness of the anal sphincter because of weak muscular contraction so can cause stool leakage. [12] In patients with multiple sclerosis, constipation and fecal incontinence often coexist, and they can be acute, chronic or intermittent due to the fluctuating ...

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