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The selection maintaining the polymorphism maximises the species' niche by expanding its feeding opportunity. The genetics of this situation cannot be clarified in the absence of a detailed breeding program, but two loci with linkage disequilibrium [40]: ch. 5 is a possibility.
In biology, polymorphism [1] is the occurrence of two or more clearly different morphs or forms, also referred to as alternative phenotypes, in the population of a species. To be classified as such, morphs must occupy the same habitat at the same time and belong to a panmictic population (one with random mating).
One example is the gene CD14, which is known to have a polymorphism that is associated with increased amounts of CD14 protein as well as reduced levels of IgE serum. [30] A study was conducted on 624 children looking at their IgE serum levels as it related to the polymorphism in CD14.
Polymorphism can be maintained by selection favoring the heterozygote, and this mechanism is used to explain the occurrence of some kinds of genetic variability. A common example is the case where the heterozygote conveys both advantages and disadvantages, while both homozygotes convey a disadvantage.
In 2015, the typical difference between an individual's genome and the reference genome was estimated at 20 million base pairs (or 0.6% of the total). [2] As of 2017, there were a total of 324 million known variants from sequenced human genomes. [3] Comparatively speaking, humans are a genetically homogeneous species.
Incomplete lineage sorting (ILS) [1] [2] [3] (also referred to as hemiplasy, deep coalescence, retention of ancestral polymorphism, or trans-species polymorphism) is a phenomenon in evolutionary biology and population genetics that results in discordance between species and gene trees.
An example would be a seemingly silent mutation in the multidrug resistance gene 1 , which codes for a cellular membrane pump that expels drugs from the cell, can slow down translation and allow the peptide chain to fold into an unusual conformation, causing the mutant pump to be less functional (in MDR1 protein e.g. C1236T polymorphism changes ...
Notable examples of systems employing polymorphic recursion include Dussart, Henglein and Mossin's binding-time analysis [2] and the Tofte–Talpin region-based memory management system. [3] As these systems assume the expressions have already been typed in an underlying type system (not necessary employing polymorphic recursion), inference can ...