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Cushing's syndrome is a collection of signs and symptoms due to prolonged exposure to glucocorticoids such as cortisol. [4] [9] [10] Signs and symptoms may include high blood pressure, abdominal obesity but with thin arms and legs, reddish stretch marks, a round red face due to facial plethora, [11] a fat lump between the shoulders, weak muscles, weak bones, acne, and fragile skin that heals ...
Moon face is often associated with Cushing's syndrome [5] [6] or steroid treatment (especially corticosteroids), which has led to it being known as Cushingoid facies. [7]Moon face is a type of corticosteroid-induced lipodystrophy along with "buffalo hump", which in one study occurred in 47% of the 820 patients.
The most common cause of Cushing syndrome is long-term, high-dose use of glucocorticoids, medications used to treat other medical conditions like asthma, rheumatoid arthritis, and lupus, the NIDDK ...
Antiglucocorticoid drugs are a treatment option for Cushing's syndrome, a condition characterized by excessive cortisol production. These medications are primarily used in two scenarios: as preoperative treatment to manage symptoms and reduce surgical risks, and as a long-term solution when surgery has failed or is not feasible.
Cushing syndrome: This condition ... Some medications and supplements can cause what’s called “drug-induced acne.” These include: Vitamin B12. Thyroid hormones. Halogen compounds (iodine ...
The symptoms of Cushing's disease are similar to those seen in other causes of Cushing's syndrome. [5] Patients with Cushing's disease usually present with one or more signs and symptoms secondary to the presence of excess cortisol or ACTH. [6] Although uncommon, some patients with Cushing's disease have large pituitary tumors (macroadenomas).
Mifepristone tablets have a marketing authorization in the United States for the treatment of high blood sugar caused by high cortisol levels in the blood (hypercortisolism) in adults with endogenous Cushing's syndrome who have type 2 diabetes mellitus or glucose intolerance and have failed surgery or cannot have surgery. [6]
[35] [36] Cushing's syndrome can either be exogenous or endogenous, depending on whether it is caused by an external or internal source, respectively. [37] The intake of glucocorticoids, a type of corticosteroid, is a common cause for the development of exogenous Cushing's syndrome. Endogenous Cushing's syndrome can occur when the body produces ...
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