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Procaine is a local anesthetic drug of the amino ester group. It is most commonly used in dental procedures to numb the area around a tooth [1] and is also used to reduce the pain of intramuscular injection of penicillin. Owing to the ubiquity of the trade name Novocain or Novocaine, in some regions, procaine is referred to generically as ...
Gerovital H3 (or procaine hydrochloride and products known as GH3 and other variants which may or may not be identical to Gerovital H3) is a preparation developed during the 1950s and promoted by its advocates as an effective anti-aging treatment. In the United States, the FDA bans Gerovital H3 from interstate commerce as an unapproved drug and ...
Heroin is commonly cut with quinine, caffeine, dimethocaine, lidocaine, procaine, lactose, inositol, dextrose, mannitol, and starch. Other opioids are sometimes sold as heroin or cut with heroin. Fentanyl sold as or laced into heroin has made the news in the past due to the numerous fatalities it causes when it appears on the market.
Procaine benzylpenicillin also known as penicillin G procaine, is an antibiotic useful for the treatment of a number of bacterial infections. [2] Specifically it is used for syphilis , anthrax , mouth infections , pneumonia , diphtheria , cellulitis , and animal bites . [ 2 ]
Dimethocaine and structurally related local anesthetics such as cocaine and procaine inhibit the uptake of dopamine (DA) by blocking dopamine transporters (DAT). [7] The dopamine transporter controls the dynamics of the neurotransmitter dopamine. This neurotransmitter controls many functions including movement, cognition and mood.
In addition, procaine can effectively restore the gene expression of tumor suppressor genes by demethylating densely hypermethylated CpG-enriched DNA. [8] For human liver cancer cells, procaine is capable of reducing tumor volume by suppressing the cell viability of HLE, HuH7, and HuH6 cells, and it has shown effective inhibition of S/G2/M ...
Diethylethanolamine reacts with 4-aminobenzoic acid to make procaine. DEAE is a precursor for DEAE-cellulose resin, which is commonly used in ion exchange chromatography. it can decrease the surface tension of water when the temperature is increased. [3] Solutions of DEAE absorb carbon dioxide (CO 2).
Procainamide is structurally similar to procaine, but in place of an ester group, procainamide contains an amide group. This substitution is the reason why procainamide exhibits a longer half-life time than procaine. [20] [21] Procainamide belongs to the aminobenzamides.
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