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It is a popular supplement taken by bodybuilders seeking to cut body fat before a competition. [27] A 2021 systematic review found that ephedrine led to a 2 kilograms (4.4 lb) weight loss greater than placebo, raised heart rate, and reduced LDL and raised HDL, with no statistically significant difference in blood pressure. [28]
Bottle of ephedrine, an alkaloid found in ephedra. Ephedra is a medicinal preparation from the plant Ephedra sinica. [1] Several additional species belonging to the genus Ephedra have traditionally been used for a variety of medicinal purposes, and are a possible candidate for the soma plant of Indo-Iranian religion. [2]
Ephedrine is the precursor of synthetic amphetamines. The diastereomer of ephedrine, pseudoephedrine is found in Ephedra sinica together along with ephedrine. Ephedrine and pseudoephedrine are both generally used for weight reduction and performance enhancement. They can also be reduced to methamphetamine. [2]
Bitter orange extract is found in citrus fruits such as Seville oranges and contains synephrine, a stimulant with effects similar to ephedrine, according to a 2017 study published in Phytotherapy ...
Fossil cones of Ephedra were found concentrated in the cemetery area, specifically within a human burial. [21] The Ephedra alkaloids, ephedrine and pseudoephedrine – constituents of E. sinica and other members of the genus – have sympathomimetic and decongestant qualities, [22] and have been used as dietary supplements, mainly for weight ...
Additionally, Ephedrine acts as an anorectic, or appetite-suppressing drug. However, the anorectic effect becomes less pronounced over time, as the body becomes tolerant of ephedrine to some degree. An estimated 75% of the efficacy of the ECA stack can be attributed to decreased appetite, while the remaining 25% is due to the thermogenic ...
Ephedrine (usually as Ephedra extract) was a common ingredient in many pre-workout supplements in the 1990s and early 2000s, sometimes in combination with caffeine and aspirin (the so-called ECA stack), however, following many reports of serious side effects and some deaths, it was banned for use in supplements by the FDA in 2004 throughout the ...
Amphetamine [note 2] (contracted from alpha-methylphenethylamine) is a central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity; it is also used to treat binge eating disorder in the form of its inactive prodrug lisdexamfetamine.