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  2. Drug interaction - Wikipedia

    en.wikipedia.org/wiki/Drug_interaction

    When two drugs affect each other, it is a drugdrug interaction (DDI). The risk of a DDI increases with the number of drugs used. [1] A large share of elderly people regularly use five or more medications or supplements, with a significant risk of side-effects from drugdrug interactions. [2] Drug interactions can be of three kinds:

  3. Risk Evaluation and Mitigation Strategies - Wikipedia

    en.wikipedia.org/wiki/Risk_Evaluation_and...

    Risk Evaluation and Mitigation Strategies (REMS) is a program of the US Food and Drug Administration for the monitoring of medications with a high potential for serious adverse effects. REMS applies only to specific prescription drugs, but can apply to brand name or generic drugs. [1] The REMS program was formalized in 2007.

  4. Pharmacotoxicology - Wikipedia

    en.wikipedia.org/wiki/Pharmacotoxicology

    Drug-drug interactions can occur when certain drugs are administered at the same time. Effects of this can be additive (outcome is greater than those of one individual drug), less than additive (therapeutic effects are less than those of one individual drug), or functional alterations (one drug changes how another is absorbed, distributed, and ...

  5. Beers criteria - Wikipedia

    en.wikipedia.org/wiki/Beers_Criteria

    [2] [3] They emphasize deprescribing medications that are unnecessary, which helps to reduce the problems of polypharmacy, drug interactions, and adverse drug reactions, thereby improving the risk–benefit ratio of medication regimens in at-risk people. [4] The criteria are used in geriatrics clinical care to monitor and improve the quality of ...

  6. Regulatory compliance - Wikipedia

    en.wikipedia.org/wiki/Regulatory_compliance

    In this context, risk-based regulation refers to the approach of identifying and assessing potential risks of money laundering and terrorist financing and implementing regulatory measures proportional to those risks. However, the shared enforcement powers between EU and national authorities in the implementation and enforcement of AML/CFT ...

  7. Network medicine - Wikipedia

    en.wikipedia.org/wiki/Network_medicine

    Moreover, such mechanism-based network pharmacology has the advantage that each of the drugs used within one module is highly synergistic, which allows for reducing the doses of each drug, which then reduces the potential of these drugs acting on other proteins outside the module and hence the chance for unwanted side effects. [19]

  8. Substance abuse prevention - Wikipedia

    en.wikipedia.org/wiki/Substance_abuse_prevention

    Rational scale to assess the harm of drugs. Substance abuse prevention, also known as drug abuse prevention, is a process that attempts to prevent the onset of substance use or limit the development of problems associated with using psychoactive substances. Prevention efforts may focus on the individual or their surroundings.

  9. Drug policy - Wikipedia

    en.wikipedia.org/wiki/Drug_policy

    A drug policy is the policy regarding the control and regulation of psychoactive substances (commonly referred to as drugs), particularly those that are addictive or cause physical and mental dependence. While drug policies are generally implemented by governments, entities at all levels (from international organisations, national or local ...