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Varenicline, sold under the brand names Chantix and Champix among others, is a medication used for smoking cessation [5] [7] and for the treatment of dry eye syndrome. [ 6 ] [ 8 ] It is a nicotinic acetylcholine receptor partial agonist .
Chantix is a prescription drug that can help people quit smoking tobacco. Medicare’s prescription drug plans include coverage for certain smoking cessation drugs, including Chantix.
The Prescribing Information follows one of two formats: "physician labeling rule" format or "old" (non-PLR) format. For "old" format labeling a "product title" may be listed first and may include the proprietary name (if any), the nonproprietary name, dosage form(s), and other information about the product.
Varenicline tartrate: Champix, Chantix 7,8,9,10-tetrahydro-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine [27] Film coated tablet Partial agonist of the nicotinic acetylcholine receptor, subtype α 4 β 2 [28] Treatment of tobacco dependence [28] Galantamine hydrobromide: Reminyl, Nivalin, Razadyne and Razadyn ER
Varenicline more than doubled the chances of quitting compared to placebo, and was also as effective as combining two types of NRT. 2 mg/day of varenicline has been found to lead to the highest abstinence rate (33.2%) of any single therapy, while 1 mg/day leads to an abstinence rate of 25.4%.
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The Recent work has demonstrated a potential role in reducing inflammatory neurotoxicity in stroke, myocardial infarction, sepsis, and Alzheimer's disease. [4] [5] [6]The α7 receptor is highly implicated in the efficacy of Varenicline for smoking cessation therapy significantly more than α4β2 which is responsible for Nicotine's rewarding effects.
For the first time in two decades, the Food and Drug Administration (FDA) has approved a new class of medication that provides an alternative to addictive opioids for patients looking to manage ...
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