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This theory is supported by the variability of clinical signs within affected cats, with many of the clinical signs being present within other feline disorders including dermatological, behavioural, orthopaedic and neurological disorders. Further support of this theory is provided by the mixed response to a wide range of therapeutic treatment.
Frunevetmab, sold under the brand name Solensia, is a monoclonal antibody used to treat pain associated with osteoarthritis in cats. [3] It is the first monoclonal antibody drug approved by the US Food and Drug Administration for animal use. [3] Frunevetmab is the international nonproprietary name. [5]
Feline odontoclastic resorption lesion (FORL) is a syndrome in cats characterized by resorption of the tooth by odontoclasts, cells similar to osteoclasts. FORL has also been called Feline tooth resorption (TR), neck lesion, cervical neck lesion, cervical line erosion, feline subgingival resorptive lesion, feline caries, or feline cavity.
Osteoarthritis is the most common form of arthritis, affecting about 237 million people or 3.3% of the world's population as of 2015. [4] [12] It becomes more common as people age. [1] Among those over 60 years old, about 10% of males and 18% of females are affected. [2] Osteoarthritis is the cause of about 2% of years lived with disability. [12]
In cervical spondylosis, a patient may be presented with dull neck pain with neck stiffness in the initial stages of the disease. As the disease progresses, symptoms related to radiculopathy (due to compression of exiting spinal nerve by narrowed intervertebral foramen) or myelopathy (due to compression on the spinal cord) can occur. [2]
No treatment is known and a poor prognosis is given. It is inherited as an autosomal recessive trait. [11] Spinal muscular atrophy occurs in cats and dogs, and is caused by the death of nerve cells in the spinal cord. This progressive disease has no known treatment and a poor prognosis.
In some, the x-ray findings may correspond to symptoms of back stiffness with flexion/extension or with mild back pain. [2] Back pain or stiffness may be worse in the morning. [ 4 ] Rarely, large anterior cervical spine osteophytes may affect the esophagus or the larynx and cause pain , difficulty swallowing [ 5 ] [ 6 ] or even dyspnea . [ 7 ]
Osteoarthritis / Degenerative Joint Disease: This is the most common type of arthritis and is a continuous decay of cartilage, caused by friction within the joints through movement. Septic arthritis / Inflammatory Joint Disease: Septic arthritis is brought upon by infection or an inherited compromised immune system and is seen in the build up ...