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The main groups of drugs involved are anti-resorptive drugs, and anti-angiogenic drugs. This condition was previously known as bisphosphonate-related osteonecrosis of the jaw ( BON or BRONJ ) because osteonecrosis of the jaw correlating with bisphosphonate treatment was frequently encountered, with its first incident occurring in 2003.
Osteoradionecrosis (ORN) is a serious complication of radiation therapy in cancer treatment where radiated bone becomes necrotic and exposed. [1] ORN occurs most commonly in the mouth during the treatment of head and neck cancer, and can arise over 5 years after radiation. [2]
Post radiation maxillary bone osteonecrosis is something that is found more in the lower jaw (mandible) rather than the maxilla (upper jaw) this is because there are many more blood vessels in the upper jaw. [7] The symptoms of this are very similar to the symptoms of medication-related osteonecrosis of the jaw (MRONJ). Patients are in a lot of ...
While DNA damage happens frequently and naturally in the cell from endogenous sources, clustered damage is a unique effect of radiation exposure. [41] Clustered damage takes longer to repair than isolated breakages, and is less likely to be repaired at all. [42] Larger radiation doses are more prone to cause tighter clustering of damage, and ...
The company promised radiantly white teeth and bacterial extraction due to the ionizing radiation of the radioactive substances. The toothpaste was considered at the time a milestone of technical achievement and was touted as a "miracle remedy". Consequential damage caused by ionizing radiation is mostly unknown.
Radiation damage is the effect of ionizing radiation on physical objects including non-living structural materials. It can be either detrimental or beneficial for materials. It can be either detrimental or beneficial for materials.
A link between these types of drugs and cognitive impairment isn't a totally new discovery, but for the first time, researchers used brain imaging techniques to determine the physical changes ...
Mouthwash and tooth brushing may have drying effects. [ 4 ] In the palliative care setting, anticholinergics and similar drugs that would normally reduce the production of saliva causing a dry mouth could be considered for symptom management: scopolamine , atropine , propantheline , hyoscine , amitriptyline , glycopyrrolate .