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Ernest Duchesne (30 May 1874 – 12 April 1912) was a French physician who noted that certain molds kill bacteria.He made this discovery 32 years before Alexander Fleming discovered the antibiotic properties of penicillin, a substance derived from those molds, but his research went unnoticed.
The history of penicillin follows observations and discoveries of evidence of antibiotic activity of the mould Penicillium that led to the development of penicillins that became the first widely used antibiotics. Following the production of a relatively pure compound in 1942, penicillin was the first naturally-derived antibiotic.
1942 – gramicidin S, the first peptide antibiotic; 1942 – sulfadimidine; 1943 – sulfamerazine; 1944 – streptomycin, the first aminoglycoside [2] 1947 – sulfadiazine; 1948 – chlortetracycline, the first tetracycline; 1949 – chloramphenicol, the first amphenicol [2] 1949 – neomycin; 1950 – oxytetracycline; 1950 – penicillin G ...
Penicillin ushered in the antibiotics revolution, with amazing results during war and peace. Science & Society Picture Library/SSPL via Getty ImagesAlbert Alexander was dying. World War II was ...
Because of this inhibition the antibiotics are most effective when the bacteria are in the logarithmic phase of growth, where then they are synthesizing the cell wall. If the bacteria are in the stationary phase of growth, then there is no wall synthesizing in progress, and the antibiotics have much lower effect. [3]
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Penicillin is an antibiotic discovered by Alexander Fleming in 1928, and its widespread use as a treatment for infections began in 1942. It is primarily used to treat bacterial infection caused by staphylococci and streptococci, and is among the first antibiotics to become highly effective. Though it still remains prevalent today, following ...
Dr. Abelardo Aguilar isolated a strain of bacteria which lead to the development of erythromycin, a broad-spectrum antibiotic used to treat and prevent a wide range of infections. [6] Eli Lilly and Company marketed erythromycin under the brand name Ilosone. [7] Aguilar received no credit or compensation for his discovery. [8] [9] [10]