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Pregabalin, sold under the brand name Lyrica among others, is an anticonvulsant, analgesic, and anxiolytic amino acid medication used to treat epilepsy, neuropathic pain, fibromyalgia, restless legs syndrome, opioid withdrawal, and generalized anxiety disorder (GAD). [13] [17] [18] Pregabalin also has antiallodynic properties.
[24] [25] Conversely, the oral bioavailability of pregabalin is greater than or equal to 90% across and beyond its entire clinical dose range (75 to 900 mg/day). [24] Food does not significantly influence the oral bioavailability of pregabalin. [24] Conversely, food increases the area-under-curve levels of gabapentin by about 10%. [24]
910 mg mL −1: Melting point: 93 to 98 °C (199 to 208 °F; 366 to 371 K) log P: ... etc. [57]) who were under prior treatment with pregabalin were transferred to ...
Hamdard Pakistan, (ہمدرد پاکستان) is a Pakistani unani medicine company which is based in Karachi, Pakistan. It was established by Hakim Said as Hamdard Laboratories (Waqf) in 1948. History
Eperisone hydrochloride is available as the brand name preparations Myonal and Epry as 50 mg sugar-coated tablets, or as 10% granules for oral administration. [6] An experimental form of the drug, as a transdermal patch system, has shown promising results in laboratory tests on rodents; however, this product is not currently available for human use.
The reuptake effects of venlafaxine are dose-dependent. At low doses (<150 mg/day), it acts only on serotonergic transmission. At moderate doses (>150 mg/day), it acts on serotonergic and noradrenergic systems, whereas at high doses (>300 mg/day), it also affects dopaminergic neurotransmission. [22]
Brivaracetam, sold under the brand name Briviact among others, is a chemical analog of levetiracetam, a racetam derivative with anticonvulsant (antiepileptic) properties. [5] [6] It has been approved since 2016.
In 2021, Malta legalized cannabis, the first EU country to do so. [75] It adopted a law echoing article 2(9) of the Single Convention (exemption for the use of drugs for industrial purposes), leading some scholars to consider it the first national legalization to achieve compliance with the drug control treaties. [52] [76]
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