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Zika fever, also known as Zika virus disease or simply Zika, is an infectious disease caused by the Zika virus. [1] Most cases have no symptoms, but when present they are usually mild and can resemble dengue fever. [1] [4] Symptoms may include fever, red eyes, joint pain, headache, and a maculopapular rash.
Rash on an arm due to Zika. Zika fever (also known as Zika virus disease) is an illness caused by Zika virus. [79] Around 80% of cases are estimated to be asymptomatic, though the accuracy of this figure is hindered by the wide variance in data quality, and figures from different outbreaks can vary significantly. [80]
In approximately one in five cases, Zika virus infections result in Zika fever, a minor illness that causes symptoms such as fever and a rash. [11] [12] Prior to the outbreak, Zika was considered a mild infection, as most infections are asymptomatic, making it difficult to determine precise estimates of the number of cases. [13]
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Zika virus vaccine clinical trials are to be conducted and established. There are efforts being put toward advancing antiviral therapeutics against zika virus for swift control. Present day Zika virus treatment is symptomatic through antipyretics and analgesics. Currently there are no publications regarding viral drug screening.
Sandfly species transmit the disease leishmaniasis, by acting as vectors for protozoan Leishmania species, and tsetse flies transmit protozoan trypansomes (Trypanosoma brucei gambiense and Trypansoma brucei rhodesiense) which cause African Trypanosomiasis (sleeping sickness). Ticks and lice form another large group of invertebrate vectors.
Zika is generally found in mosquitoes and monkeys in a band of countries stretching across equatorial Africa) [10] and Asia (Malaysia, Philippines, Thailand, Vietnam, and Indonesia). [11] [12] [13] The first confirmed case of Zika fever in a human occurs in Uganda during 1964 in a field researcher, who experiences a mild, non-itchy rash. [4]
TORCH syndrome is a cluster of symptoms caused by congenital infection with toxoplasmosis, rubella, cytomegalovirus, herpes simplex, and other organisms including syphilis, parvovirus, and Varicella zoster. [1] Zika virus is considered the most recent member of TORCH infections. [2]
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