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  2. Spinothalamic tract - Wikipedia

    en.wikipedia.org/wiki/Spinothalamic_tract

    The spinothalamic tract is a nerve tract in the anterolateral system in the spinal cord. [1] This tract is an ascending sensory pathway to the thalamus.From the ventral posterolateral nucleus in the thalamus, sensory information is relayed upward to the somatosensory cortex of the postcentral gyrus.

  3. Group C nerve fiber - Wikipedia

    en.wikipedia.org/wiki/Group_C_nerve_fiber

    The second-order neurons ascend to the brain stem and thalamus in the ventrolateral, or anterolateral, quadrant of the contralateral half of the spinal cord, forming the spinothalamic tract. [1] The spinothalamic tract is the main pathway associated with pain and temperature perception, which immediately crosses the spinal cord laterally. [1 ...

  4. Substantia gelatinosa of Rolando - Wikipedia

    en.wikipedia.org/wiki/Substantia_gelatinosa_of...

    The substantia gelatinosa is one point (the nucleus proprius being the other) where first order neurons of the spinothalamic tract synapse. Many μ and κ-opioid receptors, presynaptic and postsynaptic, are found on these nerve cells; they can be targeted to manage pain of distal origin. For instance, neuraxial administration of opioids results ...

  5. Topographic map (neuroanatomy) - Wikipedia

    en.wikipedia.org/wiki/Topographic_map_(neuroanatomy)

    The cutaneous receptors of the skin project in an orderly fashion to the spinal cord, and from there, via different afferent pathways (dorsal column-medial lemniscus tract and spinothalamic tract), to the ventral posterior nucleus of the thalamus and the primary somatosensory cortex. Again, adjacent areas on the skin are represented by adjacent ...

  6. Dorsal column–medial lemniscus pathway - Wikipedia

    en.wikipedia.org/wiki/Dorsal_column–medial...

    The dorsal column–medial lemniscus pathway (DCML) (also known as the posterior column-medial lemniscus pathway (PCML) is the major sensory pathway of the central nervous system that conveys sensations of fine touch, vibration, two-point discrimination, and proprioception (body position) from the skin and joints.

  7. Spinohypothalamic tract - Wikipedia

    en.wikipedia.org/wiki/Spinohypothalamic_tract

    The spinohypothalamic tract or spinohypothalamic fibers is a sensory fiber tract projecting from the spinal cord to the hypothalamus directly to mediate reflex autonomic and endocrine responses to painful stimuli (the hypothalamus receives additional indirect nociceptive projections from the reticular formation (see: spinoreticular tract), and periaqueductal gray (see: spinomesencephalic tract).

  8. Thalamus - Wikipedia

    en.wikipedia.org/wiki/Thalamus

    The spinothalamic tract is a sensory pathway originating in the spinal cord. It transmits information to the thalamus about pain, temperature, itch and crude touch . There are two main parts: the lateral spinothalamic tract , which transmits pain and temperature, and the anterior (or ventral) spinothalamic tract , which transmits crude touch ...

  9. Ventral posterolateral nucleus - Wikipedia

    en.wikipedia.org/wiki/Ventral_posterolateral_nucleus

    The ventral posterolateral nucleus (VPL) is one of the subdivisions of the ventral posterior nucleus in the ventral nuclear group of the thalamus. [1] It relays sensory information from the second-order neurons of the neospinothalamic tract and medial lemniscus (of the dorsal column-medial lemniscus pathway) which synapse with the third-order neurons in the nucleus.