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  2. Surfactant therapy - Wikipedia

    en.wikipedia.org/wiki/Surfactant_therapy

    Conditions adult respiratory distress syndrome or Hyaline Membrane Disease are also sometimes treated with exogenously derived surfactant. One of the more common uses of surfactant therapy is to treat alveolar surfactant deficiency in premature newborns. Most commonly, treatment is composed of multiple doses of 100 mg/kg of exogenous surfactant ...

  3. Infant respiratory distress syndrome - Wikipedia

    en.wikipedia.org/wiki/Infant_respiratory...

    Infant respiratory distress syndrome (IRDS), also known as surfactant deficiency disorder (SDD), [2] and previously called hyaline membrane disease (HMD), is a syndrome in premature infants caused by developmental insufficiency of pulmonary surfactant production and structural immaturity in the lungs.

  4. Pulmonary surfactant (medication) - Wikipedia

    en.wikipedia.org/wiki/Pulmonary_surfactant...

    Pulmonary surfactant is used as a medication to treat and prevent respiratory distress syndrome in newborn babies. [1] Prevention is generally done in babies born at a gestational age of less than 32 weeks. [1] It is given by the endotracheal tube. [1] Onset of effects is rapid. [2] A number of doses may be needed. [2]

  5. Lucinactant - Wikipedia

    en.wikipedia.org/wiki/Lucinactant

    It is a pulmonary surfactant for infants who lack enough natural surfactant in their lungs. Whereas earlier medicines of the class, such as beractant (Survanta & Beraksurf), calfactant (Infasurf), and poractant (Curosurf), are derived from animals, lucinactant is synthetic. It was approved for use in the United States by the U.S. Food and Drug ...

  6. Henrik Verder - Wikipedia

    en.wikipedia.org/wiki/Henrik_Verder

    Early treatment of premature infants with RDS using the nasal CPAP and surfactant (INSURE) method is today considered the Global Gold standard of care. Alongside his clinical achievements, Verder has also been actively involved in improving childcare and in 1975 he took the position of consultant for “ Glostrup Observation Home ” an ...

  7. Dipalmitoylphosphatidylcholine - Wikipedia

    en.wikipedia.org/wiki/Dipalmitoylphosphatidylcholine

    The treatment of preterm infants with RDS using surfactants was initially developed in the 1960s, and recent studies have demonstrated an improvement in clinical outcomes. [13] The first treatment given to some newborns with RDS was surfactant phospholipids, specifically DPPC, by means of an aerosol (Robillard, 1964).

  8. Surfactant metabolism dysfunction - Wikipedia

    en.wikipedia.org/wiki/Surfactant_metabolism...

    Testing for surfactant metabolism dysfunction should be considered for newborns with diffuse lung disease or hypoxemia, especially in families with history of neonatal lung diseases or ILD in adults. Neonatal and adult onset lung diseases with unfound causes should also be tested early for surfactant dysfunction. [ 3 ]

  9. Transient tachypnea of the newborn - Wikipedia

    en.wikipedia.org/wiki/Transient_tachypnea_of_the...

    Transient tachypnea of the newborn occurs in approximately 1 in 100 preterm infants and 3.6–5.7 per 1000 term infants. It is most common in infants born by caesarian section without a trial of labor after 35 weeks of gestation. Male infants and infants with an umbilical cord prolapse or perinatal asphyxia are at higher risk.