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  2. New Analysis Finds Millions of People on Statins May ... - AOL

    www.aol.com/lifestyle/analysis-finds-millions...

    New research finds that many people currently taking statins to lower cholesterol may not actually need this medication. An analysis, published in JAMA Internal Medicine , investigates how statin ...

  3. Lipid hypothesis - Wikipedia

    en.wikipedia.org/wiki/Lipid_hypothesis

    The lipid hypothesis (also known as the cholesterol hypothesis) is a medical theory postulating a link between blood cholesterol levels and the occurrence of cardiovascular disease. A summary from 1976 described it as: "measures used to lower the plasma lipids in patients with hyperlipidemia will lead to reductions in new events of coronary ...

  4. Statin - Wikipedia

    en.wikipedia.org/wiki/Statin

    In rabbits, liver cells sense the reduced levels of liver cholesterol and seek to compensate by synthesizing LDL receptors to draw cholesterol out of the circulation. [143] This is accomplished via proteases that cleave membrane-bound sterol regulatory element binding proteins , which then migrate to the nucleus and bind to the sterol response ...

  5. Category:Statins - Wikipedia

    en.wikipedia.org/wiki/Category:Statins

    Download as PDF; Printable version; In other projects ... Pages in category "Statins" ... out of 23 total.

  6. Fewer people may need statins to prevent heart disease, new ...

    www.aol.com/news/fewer-people-may-statins...

    In other words, as many as 4 million people in the U.S. who currently take statins for primary prevention — meaning they have not had a cardiovascular event such as a stroke or heart attack ...

  7. Statins may lower risk for heart disease and death, even in ...

    www.aol.com/lifestyle/statins-may-lower-risk...

    To find out whether statin use could help lower death risk from heart disease among older adults in these age groups, the authors of the new study analyzed electronic medical records at the Hong ...

  8. Stephen Sinatra - Wikipedia

    en.wikipedia.org/wiki/Stephen_Sinatra

    Sinatra was often critical of what he saw as an over-emphasis on cholesterol as an independent risk factor for heart disease and of what he considered the over-prescription of statin drugs. [21] Most statin drugs, which block an enzyme pathway necessary for the body to produce cholesterol, also block the enzyme pathway by which the body ...

  9. Discovery and development of statins - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    Type 2 statins Statins that are fully synthetic and have larger groups linked to the HMG-like moiety are often referred to as type 2 statins. One of the main differences between the type 1 and type 2 statins is the replacement of the butyryl group of type 1 statins by the fluorophenyl group of type 2 statins.