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Feet of a baby born to a mother who had taken thalidomide while pregnant. In the late 1950s and early 1960s, the use of thalidomide in 46 countries was prescribed to women who were pregnant or who subsequently became pregnant, and consequently resulted in the "biggest anthropogenic medical disaster ever," with more than 10,000 children born with a range of severe deformities, such as ...
In the UK, the British pharmaceutical company The Distillers Company (Biochemicals) Ltd, a subsidiary of Distillers Co. Ltd (now part of Diageo plc), marketed thalidomide throughout the UK, Australia, and New Zealand, under the brand name Distaval, as a remedy for morning sickness. Their advertisement claimed that "Distaval can be given with ...
Thalidomide had been developed by Grunenthal with whom, in July 1957, DCBL signed a sixteen-year contract to market the drug. DCBL ordered 6,000 tablets for clinical trial and 500 grammes of pure substance for animal experiments and formulation. Thalidomide was marketed in the United Kingdom under the name Distaval, beginning on 14 April 1958.
Alexander Leslie Florence, also called Leslie Florence (1927 – 26 March 2018) was a Scottish general practitioner, known for his letter on his observations of neurological side effects of thalidomide, published on 31 December 1960 in the British Medical Journal, and noticed by Frances Kelsey. [1] [2] [3]
The Committee on Safety of Medicines (CSM) was an independent advisory committee that advised the UK Licensing Authority on the quality, efficacy, and safety of medicines. Following the thalidomide tragedy of 1957 to 1961, in 1963 the government asked Sir Derrick Dunlop to set up a committee to investigate the control and introduction of new ...
Lorraine Mercer MBE is a British thalidomide survivor, painter, lace maker, and carriage driver with the RDA. Mercer was a representative of the global thalidomide community as a bearer of the Olympic Torch in 2012 for her country. [1] [2] Her chariot was adapted to carry the Olympic torch safely above her head away from the oxygen she needs.
On Giant's Shoulders is a 1979 BBC television film about the early life of thalidomide victim Terry Wiles, with Wiles playing himself. The drama also starred Bryan Pringle and Judi Dench and won an Emmy Award in 1980. [1] [2]
The scheme was founded in 1964 after the thalidomide disaster, and was developed by Bill Inman.It is run by the Medicines and Healthcare products Regulatory Agency (MHRA) and the Commission on Human Medicines.