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In 1986, it was presumed that permanent brain damage may result from chronic use of benzodiazepines similar to alcohol-related brain damage. [70] In 1987, 17 inpatient people who used high doses of benzodiazepines non-medically have anecdotally shown enlarged cerebrospinal fluid spaces with associated cerebral atrophy. Cerebral atrophy ...
Certain antidepressants may cause emotional blunting, characterized by reduced intensity of both positive and negative emotions as well as symptoms of apathy, indifference, and amotivation. [ 82 ] [ 83 ] It may be experienced as either beneficial or detrimental depending on the situation. [ 84 ]
Some antidepressants, including commonly prescribed ones from the class known as SSRIs (selective serotonin reuptake inhibitors), can cause sexual side effects such as erectile dysfunction ...
The cause of serotonin toxicity or accumulation is an important factor in determining the course of treatment. Serotonin is catabolized by monoamine oxidase A in the presence of oxygen , so if care is taken to prevent an unsafe spike in body temperature or metabolic acidosis, oxygenation will assist in dispatching the excess serotonin.
They can kill your libido, make orgasm impossible, and may cause a host of other side effects including weight gain, dry mouth, and diarrhea. For all these reasons, it’s critical to find drugs ...
The risk of liver damage appears to be only for patients already at risk, unlike the antidepressant nefazodone, which, though rare, can spontaneously cause liver failure in healthy patients. [13] Duloxetine is also approved for major depressive disorder (MDD), generalized anxiety disorder (GAD), diabetic neuropathy, chronic musculoskeletal pain ...
A healthcare professional can ask you about your symptoms to determine which antidepressant is right for you. There are many types of antidepressants. There’s no one-size-fits-all option when it ...
Tricyclics and SSRI can cause the so-called drug-induced QT prolongation, especially in older adults; [131] this condition can degenerate into a specific type of abnormal heart rhythm called Torsades de points, which can potentially lead to sudden cardiac arrest. [132] Some antidepressants are also believed to increase thoughts of suicidal ...
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