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In analytical chemistry, the detection limit, lower limit of detection, also termed LOD for limit of detection or analytical sensitivity (not to be confused with statistical sensitivity), is the lowest quantity of a substance that can be distinguished from the absence of that substance (a blank value) with a stated confidence level (generally 99%).
A blank value in analytical chemistry is a measurement of a blank. The reading does not originate from a sample, but the matrix effects , reagents and other residues . These contribute to the sample value in the analytical measurement and therefore have to be subtracted.
A calibration curve plot showing limit of detection (LOD), limit of quantification (LOQ), dynamic range, and limit of linearity (LOL).. In analytical chemistry, a calibration curve, also known as a standard curve, is a general method for determining the concentration of a substance in an unknown sample by comparing the unknown to a set of standard samples of known concentration. [1]
A blank solution is a solution containing little to no analyte of interest, [1] usually used to calibrate instruments such as a colorimeter. According to the EPA, the "primary purpose of blanks is to trace sources of artificially introduced contamination." [2] Different types of blanks are used to identify the source of contamination in the ...
A minimum detectable signal is a signal at the input of a system whose power allows it to be detected over the background electronic noise of the detector system. It can alternately be defined as a signal that produces a signal-to-noise ratio of a given value m at the output.
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The Bekenstein bound limits the amount of information that can be stored within a spherical volume to the entropy of a black hole with the same surface area. Thermodynamics limit the data storage of a system based on its energy, number of particles and particle modes. In practice, it is a stronger bound than the Bekenstein bound.
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