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  2. Dextran - Wikipedia

    en.wikipedia.org/wiki/Dextran

    Dextran is used to make microcarriers for industrial cell culture; Orally-administered dextran sodium sulphate is used to induce colitis in animal models of inflammatory bowel disease. [12] Dextran is a common model compound to test the potential of drug formulations to facilitate intestinal absorption via the paracellular route. [13]

  3. Dextran drug delivery systems - Wikipedia

    en.wikipedia.org/wiki/Dextran_drug_delivery_systems

    Dextran prodrugs are chemically linked drug-polymer complexes in which enzymatic processes and hydrolysis in vivo cause the drug to become pharmacologically active. Therapeutic agents can be linked to dextran via an ester bond which can be hydrolyzed slowly by esterases to produce sustained, stable drug release.

  4. Acetalated dextran - Wikipedia

    en.wikipedia.org/wiki/Acetalated_dextran

    Acetalated dextran's degradation time can vary from hours to a month or more at pH 7.2. [4] [5] [6] Also, acetalated dextran is unique because it is acid sensitive. Therefore, at lower pH acetalated dextran degrades more rapidly, which results in a polymer that degrades approximately two logs faster at pH 5 compared to pH 7.

  5. Sephadex - Wikipedia

    en.wikipedia.org/wiki/Sephadex

    Sephadex is a cross-linked dextran gel used for gel filtration. It was launched by Pharmacia in 1959, after development work by Jerker Porath and Per Flodin. [1] [2] The name is derived from separation Pharmacia dextran. It is normally manufactured in a bead form and most commonly used for gel filtration columns. By varying the degree of cross ...

  6. Emulsion stabilization using polyelectrolytes - Wikipedia

    en.wikipedia.org/wiki/Emulsion_stabilization...

    Polyelectrolytes such as dextran sulfate (DSS), protamine (PRM) or poly-L-arginine all fulfill these requirements and may be used as a capsule with an emulsion inside. [22] Oil in water emulsions are currently used as safe solvents for vaccines. [23] It is important that these emulsion are stable and remain so for long periods of time ...

  7. Dextranomer - Wikipedia

    en.wikipedia.org/wiki/Dextranomer

    Dextranomer (trade name Debrisan, Exudex [1]) is a cicatrizant used in dressings for wound healing, [2] and in pharmaceutical products to treat fecal incontinence. [3] It consists of dextran polymer chains cross-linked into a three-dimensional network. [4]

  8. Dextran sulphate sodium - Wikipedia

    en.wikipedia.org/wiki/Dextran_sulphate_sodium

    Dextran sulphate sodium (DSS), or dextran sodium sulphate (or any of the former with "sulfate") is a synthetic sulphated polysaccharide with anticoagulant activity used in immunological research to induce colitis. [1] [2] Dextran polymer molecules with a molecular weight of 36–50 kDa are frequently used to this end. [2]

  9. Diethylaminoethyl cellulose - Wikipedia

    en.wikipedia.org/wiki/Diethylaminoethyl_cellulose

    Cellulose, dextran, agarose, and other insoluble complexes are unaffected because they compose inert matrices, hence why they are so often derivatized with strong and weak cation and anion exchangers in chromatography. DEAE-C beads have diethylaminoethyl chains covalently bound to oxygen atoms on the D-glucose subunits of cellulose.

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