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Varenicline, sold under the brand names Chantix and Champix among others, is a medication used for smoking cessation [5] [7] and for the treatment of dry eye syndrome. [ 6 ] [ 8 ] It is a nicotinic acetylcholine receptor partial agonist .
A 2013 meta-analysis of eight studies demonstrated that cytisine has similar effectiveness to varenicline but with substantially lower side effects. [13] A 2014 systematic review and economic evaluation concluded that cytisine was more likely to be cost-effective for smoking cessation than varenicline .
There are many adverse effects, interactions and contraindications for antinicotinic and antimuscarinic agents. Adverse effects include hypotension, dry mouth, dry eyes etc. They interact with grapefruit juice and various medications, e.g. warfarin, metoclopramide. Therefore, cautions should be exercised and advice from medical professionals ...
Contraindications include asthma and angle closure glaucoma. [citation needed] Mechanism of action. Cevimeline is a cholinergic agonist. [2]
Varenicline tartrate: Champix, Chantix 7,8,9,10-tetrahydro-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine [27] Film coated tablet Partial agonist of the nicotinic acetylcholine receptor, subtype α 4 β 2 [28] Treatment of tobacco dependence [28] Galantamine hydrobromide: Reminyl, Nivalin, Razadyne and Razadyn ER
Trimetaphan camsilate or trimethaphan camsylate (), trade name Arfonad, is a sympatholytic drug used in rare circumstances to lower blood pressure.. Trimetaphan is a ganglionic blocker: it counteracts cholinergic transmission at a specific type of nicotinic acetylcholine receptors in the autonomic ganglia and therefore blocks both the sympathetic nervous system and the parasympathetic nervous ...
There are few interactions between nicotine and prescription medications (e.g., adenosine, cimetidine, varenicline), but the act of quitting smoking can impact the effect of other medications. [4] Some of the medications are: [5] Antipsychotic medications; Heart-related medications; Caffeine
In medicine, a contraindication is a condition (a situation or factor) that serves as a reason not to take a certain medical treatment due to the harm that it would cause the patient. [ 1 ] [ 2 ] Contraindication is the opposite of indication , which is a reason to use a certain treatment.