Search results
Results from the WOW.Com Content Network
Aging has been attributed to molecular cross-linking (Bjorksten, 1968), free radical-induced damages (Harman, 1993), changes in immunological functions (Effros, 2005), telomere shortening (Kruk et al., 1995) and the presence of senescence genes in the DNA (Warner et al., 1987).
Theories of aging can be divided into two categories: those that answer the question “Why do we age?” and those that address the. question “How do we age?” Only a few broad, overarching theories attempt to explain why we and nearly all living organisms age.
A number of theories, which fall into two main categories, have been proposed in an attempt to explain the process of aging. The first category is comprised of concepts holding that aging is programmed and those positing that aging is caused by the accumulation of damage.
Three major psychosocial theories have been proposed to attempt to explain successful aging. These include the activity theory, disengagement theory and the continuity theory.
Modern biological theories of aging in humans fall into two main categories: programmed and damage or error theories. The programmed theories imply that aging follows a biological timetable, perhaps a continuation of the one that regulates childhood growth and development.
In this review, we attempted to summarize the current theories of aging and the approaches to understanding it. Keywords: accumulation of damage; advanced glycation end-product; aging; life expectancy; reactive oxygen species; telomerase.
There are countless theories as to why and how we age, but, until recently, the very definition of aging – senescence – was still uncertain. Here, we summarize the main views of the different models of senescence, with a special emphasis on the biochemical processes that accompany aging.
The seminal mechanistic theories of processing speed, limited resources, and inhibitory deficits are discussed and viewed as especially important theories for understanding age-related memory decline.
This video looks 12 theories current on the causes of ageing, namely: Genome damage to DNA; Telemere shortening; epigenetic malfunctions; Misfolding of proteins; Cell senescence; Stem cell exhaustion; Glycation; AMPK pathways; Inflammaging; MTOR pathways; Sirtuins (longivity genes). Some of these theories are outlined later.
There are two primary categories of aging theories which differ fundamentally in what can be referred to as the "purpose" of aging. In the first category, aging is essentially an accident; an accumulation of damage and wear and tear to the body which eventually leads to death.