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Chemotherapy-induced peripheral neuropathy is a progressive, enduring and often irreversible tingling numbness, intense pain, and hypersensitivity to cold, beginning in the hands and feet and sometimes involving the arms and legs caused by some chemotherapy agents. [7]
Paresthesia is a sensation of the skin that may feel like numbness (technically called hypoesthesia), tingling, pricking, chilling, or burning. [1] It can be temporary or chronic and has many possible underlying causes. [1] Paresthesia is usually painless and can occur anywhere on the body, but most commonly in the arms and legs. [1]
Peripheral neuropathy may first be considered when an individual reports symptoms of numbness, tingling, and pain in feet. After ruling out a lesion in the central nervous system as a cause, a diagnosis may be made on the basis of symptoms, laboratory and additional testing, clinical history, and a detailed examination.
Paresthesia refers to the tingling, pricking, “pins and needles” sensation that occurs beneath the skin, according to the Cleveland Clinic. If you’ve ever “slept” on your hand, arm or ...
That can cause tingling or numbness in the hands, arms, legs, and feet. “ The mechanism is not well understood but it could involve the direct toxic effect of alcohol on nerve fibers,” Dr ...
A nerve condition, vitamin deficiency, or injury might be to blame for tingling in feet. Experts share other common causes for tingling feet, plus when to see a doctor.
The causes of nerve damage are grouped into categories including those due to paraneoplastic causes (neuropathy secondary to cancer), immune mediated, infectious, inherited or degenerative causes and those due to toxin exposure. In idiopathic sensory neuronopathy no cause is identified. Idiopathic causes account for about 50% of cases. [2]
Sensory nerve entrapment presents with paresthesias. These paresthesias may be painful, such as shooting pain, burning, or a dull ache. They may also be pain-free, such as numbness or tingling. Motor nerve entrapment may present with muscle weakness or paralysis for voluntary movements of the innervated muscles.