Search results
Results from the WOW.Com Content Network
Here are some ways nanomaterials are used in cancer treatment: [1] Nano-materials Aerosol Drug delivery systems: Nanoparticles can be loaded with anticancer drugs, improving drug solubility, stability, and targeted delivery to cancer cells. This enhances the drug's therapeutic effect while reducing side effects on healthy tissues. [2]
The overall drug consumption and side-effects may be lowered significantly by depositing the active pharmaceutical agent in the diseased region only and in no higher dose than needed. Targeted drug delivery is intended to reduce the side effects of drugs in tandem decreases in consumption and treatment expenses.
Targeted delivery is believed to improve efficacy while reducing side-effects. When implementing a targeted release system, the following design criteria for the system must be taken into account: the drug properties, side-effects of the drugs, the route taken for the delivery of the drug, the targeted site, and the disease.
Development of solid lipid nanoparticles is one of the emerging fields of lipid nanotechnology (for a review on lipid nanotechnology, see [16]) with several potential applications in drug delivery, clinical medicine and research, as well as in other disciplines. Due to their unique size-dependent properties, lipid nanoparticles can possibly ...
It can be directed to the location of cancer cells with sustained release behavior. Studies have also been done on gold nanoparticle responses to local near-infrared (NIR) light as a stimuli for drug release. In one study, gold nanoparticles functionalized with double-stranded DNA encapsulated with drug molecules, were irradiated with NIR light.
The health and safety hazards of nanomaterials include the potential toxicity of various types of nanomaterials, as well as fire and dust explosion hazards. Because nanotechnology is a recent development, the health and safety effects of exposures to nanomaterials, and what levels of exposure may be acceptable, are subjects of ongoing research.
Traditionally, LNPs are composed of four indispensable lipid components: an ionizable amino lipid that aids in both escaping the endosomes and binding nucleic acids to the particle, an amphipathic phospholipid that promotes fusion with the target cell and endosomes, cholesterol to enhance nanoparticle stability, and a polyethylene glycol lipid ...
SLNs can be made by replacing the liquid lipid oil used in the emulsion process with a solid lipid. In solid lipid nanoparticles, the drug molecules are dissolved in the particle's solid hydrophobic lipid core, this is called the drug payload, and it is surrounded by an aqueous solution. [6]