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For acute pericarditis to formally be diagnosed, two or more of the following criteria must be present: chest pain consistent with a diagnosis of acute pericarditis (sharp chest pain worsened by breathing in or a cough), a pericardial friction rub, a pericardial effusion, and changes on electrocardiogram (ECG) consistent with acute pericarditis ...
[4] [5] Diagnosis is based on the presence of chest pain, a pericardial rub, specific electrocardiogram (ECG) changes, and fluid around the heart. [6] A heart attack may produce similar symptoms to pericarditis. [1] Treatment in most cases is with NSAIDs and possibly the anti-inflammatory medication colchicine. [6]
Treatment for purulent pericarditis consists of two main components. [3] Antimicrobial therapy. Empiric intravenous antimicrobial therapy is recommended as soon as a diagnosis of purulent pericarditis is suspected. [3] Pericardial drainage. There are several therapeutic mechanisms that can be used to drain purulent fluid from the pericardial sac.
Constrictive pericarditis is a condition characterized by a thickened, fibrotic pericardium, limiting the heart's ability to function normally. [1] In many cases, the condition continues to be difficult to diagnose and therefore benefits from a good understanding of the underlying cause.
Uremic pericarditis is associated with azotemia, and occurs in about 6-10% of kidney failure patients. BUN is normally >60 mg/dL (normal is 7–20 mg/dL). However, the degree of pericarditis does not correlate with the degree of serum BUN or creatinine elevation. The pathogenesis is poorly understood. [2]
Tuberculous pericarditis is an under-diagnosed condition. [3] Diagnosis often requires a range of diagnostic tools, including pericardiocentesis, biochemical tests, and imaging. [3] [4] Treatment of this disease is similar to treatment of pulmonary tuberculosis. [1] [4] Alternative treatment options to reduce cardiac complications are also ...
Pericarditis or pleuritis or both Molecular Criterion: NOD2 IVS8+158 or R702W or both, or other rare variants Exclusion Criteria: High titer antinuclear antibodies, inflammatory bowel disease, Blau syndrome, adult sarcoidosis, primary Sjögren syndrome and monogenic autoinflammatory diseases
Important etiologies of pericardial effusions are inflammatory and infectious (pericarditis), neoplastic, traumatic, and metabolic causes. Echocardiogram, CT and MRI are the most common methods of diagnosis, although chest X-ray and EKG are also often performed. Pericardiocentesis may be diagnostic as well as therapeutic (form of treatment).
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