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The base of a hair's root (the "bulb") contains the cells that produce the hair shaft. [12] Other structures of the hair follicle include the oil producing sebaceous gland which lubricates the hair and the arrector pili muscles, which are responsible for causing hairs to stand up.
Diagram of the hair shaft, indicating medulla (innermost), cortex, and cuticle (exterior.) Anatomy of hair. The cortex of the hair shaft is located between the hair cuticle and medulla and is the thickest hair layer. It contains most of the hair's pigment, giving the hair its color. The major pigment in the cortex is melanin, which is also ...
The hair follicle is an organ found in mammalian skin. [1] It resides in the dermal layer of the skin and is made up of 20 different cell types, each with distinct functions.. The hair follicle regulates hair growth via a complex interaction between hormones, neuropeptides, and immune cells
The scalp is the area of the head where head hair grows. [1] It is made up of skin, layers of connective and fibrous tissues, and the membrane of the skull. Anatomically, the scalp is part of the epicranium, a collection of structures covering the cranium.
KRT81, a type II hair keratin, is a major hair protein expressed in the hair cortex. Interestingly, despite being typically associated with hair structures, KRT81 expression has been observed in the SKBR3 human breast cancer cell line and metastatic lymph nodes of breast carcinomas, but not in normal breast epithelial cells.
Relative to keratinocytes that make up the hair follicle, sebaceous glands are composed of huge cells with many large vesicles that contain the sebum. [8] These cells express Na + and Cl − ion channels, ENaC and CFTR (see Fig. 6 and Fig. 7 in reference [8]). Sebaceous glands secrete the oily, waxy substance called sebum (Latin: fat, tallow ...
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Damage to hair cells can cause damage to the vestibular system and therefore cause difficulties in balancing. However, other vertebrates, such as the frequently studied zebrafish, and birds have hair cells that can regenerate. [5] [6] The human cochlea contains on the order of 3,500 inner hair cells and 12,000 outer hair cells at birth. [7]