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In physiology, a stimulus [1] is a change in a living thing's internal or external environment. This change can be detected by an organism or organ using sensitivity, and leads to a physiological reaction. [ 2 ]
Two-alternative forced choice (2AFC) is a method for measuring the sensitivity of a person or animal to some particular sensory input, stimulus, through that observer's pattern of choices and response times to two versions of the sensory input. For example, to determine a person's sensitivity to dim light, the observer would be presented with a ...
Stimulus filtering occurs when an animal's nervous system fails to respond to stimuli that would otherwise cause a reaction to occur. [1] The nervous system has developed the capability to perceive and distinguish between minute differences in stimuli, which allows the animal to only react to significant impetus. [ 2 ]
The stimulation of a mechanoreceptor causes mechanically sensitive ion channels to open and produce a transduction current that changes the membrane potential of the cell. [10] Typically the mechanical stimulus gets filtered in the conveying medium before reaching the site of mechanotransduction. [11]
Let denote the spatio-temporal stimulus vector preceding the 'th time bin, and the spike count in that bin. The stimuli can be assumed to have zero mean (i.e., [] =).If not, it can be transformed to have zero-mean by subtracting the mean stimulus from each vector.
In molecular biology, ultrasensitivity describes an output response that is more sensitive to stimulus change than the hyperbolic Michaelis-Menten response. Ultrasensitivity is one of the biochemical switches in the cell cycle and has been implicated in a number of important cellular events, including exiting G2 cell cycle arrests in Xenopus ...
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The random sequences are presented to the subject several times. The strength of the stimulus, perceived in more than half of the presentations, will be taken as the threshold. Adaptive method: Stimulation starts with a surely supra-threshold stimulus; then further stimuli are given with an intensity decreased in previously-defined steps.