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Lennon wrote "How Do You Sleep?" in the aftermath of Paul McCartney's successful lawsuit in the London High Court to dissolve the Beatles as a legal partnership. [1] This ruling was caused by the publication of Lennon's remarks about the Beatles in a December 1970 interview with Rolling Stone magazine, and McCartney and his wife taking full-page advertisements in the music press, in which, as ...
However, most antidepressant treatments do not directly enhance DA neurotransmission, which may contribute to residual symptoms, including impaired motivation, concentration, and pleasure. [ 21 ] Preclinical and clinical research indicates that drugs inhibiting the reuptake of all three of these neurotransmitters can produce a more rapid onset ...
This translates to the 2nd- and 3rd-most-common antidepressants, behind Lexapro (escitalopram), an SSRI. [87] In some studies, SNRIs demonstrated slightly higher antidepressant efficacy than the SSRIs (response rates 63.6% versus 59.3%). [43] However, in one study escitalopram had a superior efficacy profile to venlafaxine. [88]
A study finds that antidepressants don’t boost the feel-good brain chemical serotonin, as previously thought. Here’s what you need to know.
Noradrenergic and specific serotonergic antidepressants (NaSSAs) are a class of psychiatric drugs used primarily as antidepressants. [1] They act by antagonizing the α 2 -adrenergic receptor and certain serotonin receptors such as 5-HT 2A and 5-HT 2C , [ 1 ] but also 5-HT 3 , [ 1 ] 5-HT 6 , and/or 5-HT 7 in some cases.
Having said that, you can walk into your local pharmacy and pick up an over-the-counter (OTC) antidepressant alternative with the same ease you can pick up a bag of chips or a tube of toothpaste.
A 2012 review focused on antidepressants and sleep found that mirtazapine reduced the time it took to fall asleep and improved the quality of sleep in many people with sleep disorders caused by depression, but that it could also disturb sleep in many people, especially at higher doses, causing restless leg syndrome in 8 to 28% of people and in ...
One of the best things you can do for your mental health, per a psychologist who counsels U.S. Olympians. Even Olympians battle impostor syndrome. How one Team USA psychologist is supporting ...