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A toxicologist working in a lab (United States, 2008)Toxicology is a scientific discipline, overlapping with biology, chemistry, pharmacology, and medicine, that involves the study of the adverse effects of chemical substances on living organisms [1] and the practice of diagnosing and treating exposures to toxins and toxicants.
A threshold model used in toxicology posits that anything above a certain dose of a toxin is dangerous, and anything below it safe. This model is usually applied to non-carcinogenic health hazards. Edward J. Calabrese and Linda A. Baldwin wrote: The threshold dose-response model is widely viewed as the most dominant model in toxicology. [6]
Ambiguity effect; Assembly bonus effect; Audience effect; Baader–Meinhof effect; Barnum effect; Bezold effect; Birthday-number effect; Boomerang effect; Bouba/kiki effect
Similarly, physiological toxicokinetic models are physiological pharmacokinetic models developed to describe and predict the behavior of a toxicant in an animal body; for example, what parts (compartments) of the body a chemical may tend to enter (e.g. fat, liver, spleen, etc.), and whether or not the chemical is expected to be metabolized or ...
Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism. [1] Toxicity can refer to the effect on a whole organism, such as an animal, bacterium, or plant, as well as the effect on a substructure of the organism, such as a cell (cytotoxicity) or an organ such as the liver (hepatotoxicity).
Toxicology testing, also known as safety assessment, or toxicity testing, is the process of determining the degree to which a substance of interest negatively impacts the normal biological functions of an organism, given a certain exposure duration, route of exposure, and substance concentration.
A drug test (also often toxicology screen or tox screen) is a technical analysis of a biological specimen, for example urine, hair, blood, breath, sweat, or oral fluid/saliva—to determine the presence or absence of specified parent drugs or their metabolites.
Toxinology is a subfield of toxicology dedicated to toxic substances produced by or occurring in living organisms. [1] [2] References This page was last edited on 22 ...