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Rabies is a viral disease that causes encephalitis in humans and other mammals. [1] It was historically referred to as hydrophobia ("fear of water") because its victims would panic when offered liquids to drink. Early symptoms can include fever and abnormal sensations at the site of exposure. [1]
After exposure to rabies, there is no contraindication to its use, because the untreated virus is virtually 100% fatal. [11] [13] The first rabies vaccine was introduced in 1885 and was followed by an improved version in 1908. [14] Over 29 million people worldwide receive human rabies vaccine annually. [15]
The plaque reduction neutralization test is used to quantify the titer of neutralizing antibody for a virus. [1] [2] The serum sample or solution of antibody to be tested is diluted and mixed with a viral suspension. This is incubated to allow the antibody to react with the virus. This is poured over a confluent monolayer of host cells.
What they look like: Chiggers, a type of small mite, typically leave clusters of bites that are often very itchy. In many cases, chigger bites appear as small, red and itchy bumps. Sometimes, they ...
The typical way to figure out if an animal that bit you has rabies is to kill it, cut off its head and express ship it-- unfrozen--to your state health department for a test that will take 10 to ...
Lyssavirus (from the Greek λύσσα lyssa "rage, fury, rabies" and the Latin vīrus) [1] [2] is a genus of RNA viruses in the family Rhabdoviridae, order Mononegavirales. Mammals, including humans, can serve as natural hosts. [3] [4] The genus Lyssavirus includes the causative agent (rabies virus) of rabies. [5]
3D still showing rabies virus structure. Rhabdoviruses have helical symmetry, so their infectious particles are approximately cylindrical in shape. They are characterized by an extremely broad host spectrum ranging from plants [citation needed] to insects [citation needed] and mammals; human-infecting viruses more commonly have icosahedral symmetry and take shapes approximating regular polyhedra.
Negri was convinced the inclusions were a parasitic protozoon and the etiologic agent of rabies. Later that same year, however, Paul Remlinger and Rifat-Bey Frasheri in Constantinople and, separately, Alfonso di Vestea in Naples showed that the etiologic agent of rabies is a filterable virus. Negri continued until 1909 to try to prove that the ...