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Marjolin's ulcer refers to an aggressive ulcerating squamous cell carcinoma presenting in an area of previously traumatized, [1] chronically inflamed, [2] or scarred skin. [3]: 737 [4] They are commonly present in the context of chronic wounds including burn injuries, varicose veins, venous ulcers, [5] ulcers from osteomyelitis, [6] and post radiotherapy scars.
Infiltrative or morpheaform basal-cell cancers can present as a skin thickening or scar tissue – making diagnosis difficult without using tactile sensation and a skin biopsy. It is often difficult to visually distinguish basal-cell cancer from acne scar, actinic elastosis, and recent cryodestruction inflammation. [14]
Though 80–90 percent of cancer pain can be eliminated or well controlled, nearly half of all people with cancer pain in the developed world and more than 80 percent of people with cancer worldwide receive less than optimal care. [28] Cancer changes over time, and pain management needs to reflect this.
A technique called pleurodesis can be used to intentionally create scar tissue within the pleural space, usually as a treatment for repeated episodes of a punctured lung, known as a pneumothorax, or for pleural effusions caused by cancer. While this procedure usually generates only limited scar tissue, in rare cases a fibrothorax can develop. [6]
This occurs as a reaction to tissue damage, [1] including as a consequence of medical device implantation. Dystrophic calcification can occur even if the amount of calcium in the blood is not elevated, in contrast to metastatic calcification , which is a consequence of a systemic mineral imbalance, including hypercalcemia and/or ...
Scar revision is a process of cutting the scar tissue out. After the excision, the new wound is usually closed up to heal by primary intention, instead of secondary intention. Deeper cuts need a multilayered closure to heal optimally, otherwise depressed or dented scars can result. [57]
Olivia Munn opened up about how she hid her double mastectomy scars amid her battle with breast cancer. “I have some divots and dents on one side of my body near where the lymph nodes were, and ...
The heterogeneity of tumor cancer cells and stroma cells combined with the complexities of surrounding connective tissue suggest that understanding cancer by tumor cell genomic analysis is not sufficient; [4] analyzing the cells together with the surrounding stromal tissue may provide more comprehensive and meaningful data.