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Phenylbiguanide (PBG) is a 5-HT3 agonist used to study the role of 5-HT3 receptors in the central nervous system. [1] It has been found to trigger dopamine release in the nucleus accumbens of rats. [ 2 ]
Biguanide (/ b aɪ ˈ ɡ w ɒ n aɪ d /) is the organic compound with the formula HN(C(NH)NH 2) 2. It is a colorless solid that dissolves in water to give a highly basic solution. It is a colorless solid that dissolves in water to give a highly basic solution.
meta-Chlorophenylbiguanide (1-(3-Chlorophenylbiguanide, m-CPBG) is an allosteric agonist and modulator of the 5-HT 3 receptor [1] [2] [3] and an antagonist of the α 2A-adrenergic receptor. [4] It has anxiogenic , emetic and hypothermic effects in animal studies.
The hydrocarbon group is a 4-(1,1,3,3-tetramethylbutyl)-phenyl group. Triton X-100 is closely related to IGEPAL CA-630, which might differ from it mainly in having slightly shorter ethylene oxide chains. As a result, Triton X-100 is slightly more hydrophilic than Igepal CA-630 thus these two detergents may not be considered functionally ...
SB-357134 is a drug which is used in scientific research. It acts as a potent, selective and orally active 5-HT 6 receptor antagonist. [1] SB-357134 and other 5-HT 6 antagonists show nootropic effects in animal studies, [2] [3] [4] and have been proposed as potential novel treatments for cognitive disorders such as schizophrenia and Alzheimer's disease.
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Shows the oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB) to 3,3',5,5'-tetramethylbenzidine diimine. The resulting one-electron oxidation product is a diimine-diamine complex, which causes the solution to take on a blue colour, [2] and this colour change can be read on a spectrophotometer at the wavelengths of 370 and 650 nm.
Chemical formula (C 8 H 17 N 5) n Pharmacology ATC code. D08AC05 S01AX24 ... The PHMB hydrochloride salt (solution) is used in the majority of formulations.
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