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Name Description Knots [Note 1]Links References trRosettaRNA: trRosettaRNA is an algorithm for automated prediction of RNA 3D structure. It builds the RNA structure by Rosetta energy minimization, with deep learning restraints from a transformer network (RNAformer). trRosettaRNA has been validated in blind tests, including CASP15 and RNA-Puzzles, which suggests that the automated predictions ...
The ViennaRNA Package is software, a set of standalone programs and libraries used for predicting and analysing RNA nucleic acid secondary structures. [1] The source code for the package is released as free and open-source software and compiled binaries are available for the operating systems Linux, macOS, and Windows.
The Nussinov algorithm is a nucleic acid structure prediction algorithm used in computational biology to predict the folding of an RNA molecule that makes use of dynamic programming principles. [1] The algorithm was developed by Ruth Nussinov in the late 1970s.
Program to recognize vertebrate RNA polymerase II promoters: Vertebrates [7] EasyGene: The gene finder is based on a hidden Markov model (HMM) that is automatically estimated for a new genome. Prokaryotes [8] [9] EuGene: Integrative gene finding: Prokaryotes, Eukaryotes [10] [11] FGENESH: HMM-based gene structure prediction: multiple genes ...
Center for non-coding RNA in Technology and Health, University of Copenhagen: Yes Yes Yes All Yes NGG, NGA, NAG Yes Yes , [3] [4] Invitrogen TrueDesign Genome Editor Thermo Fisher Scientific: Yes Yes No 3 No NGG Yes Yes [5] Breaking-Cas Spanish National Center for Biotechnology: Yes (over 1000 genomes) Yes Yes (by weights) 4 No User ...
Multiple alignment and secondary structure prediction: RNA: Local or global: I. Holmes: 2005: Free, GPL 3 (parte de DART) T-Coffee: More sensitive progressive alignment: Both: Local or global: C. Notredame et al. 2000 (newest version 2008) Free, GPL 2 UGENE: Supports multiple alignment with MUSCLE, KAlign, Clustal and MAFFT plugins: Both: Local ...
The simplest way to find the lowest free energy structure would be to generate all possible structures and calculate the free energy for it, but the number of possible structures for a sequence increases exponentially with the length of RNA: number of secondary structures = (1,8) N, N- number of nucleotides. [6]
The genomic RNA of retroviruses is linked non-covalently to the dimer linkage structure (DLS), a non-coding region in the 5' UTR. For the kissing loop interaction to occur, there is a triple interaction that involves a 5'-flanking purine and 2 centralized bases in the complementary strand.