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Adjuvant chemotherapy has been used in malignant melanoma, but there is little hard evidence to use chemotherapy in the adjuvant setting. However, melanoma is not a chemotherapy-resistant malignancy. Dacarbazine, temozolomide, and cisplatin all have a reproducible 10–20% response rate in metastatic melanoma.
[2] [6] Due to the rarity of this tumor and variability in clinical and histological presentation, SGc is often misdiagnosed as an inflammatory condition or a more common neoplasm. [6] SGc is commonly treated with wide local excision or Mohs micrographic surgery , and the relative survival rates at 5 and 10 years are 92.72 and 86.98%, respectively.
Chemotherapy may be given with a curative intent (which almost always involves combinations of drugs), or it may aim only to prolong life or to reduce symptoms (palliative chemotherapy). Chemotherapy is one of the major categories of the medical discipline specifically devoted to pharmacotherapy for cancer, which is called medical oncology. [1] [2]
Post-surgical adjuvant treatment may be recommended. [29] Lymph node metastases are rare, and routine lymph node removal is typically unnecessary. [ 30 ] Laparoscopic surgery , a minimally invasive abdominal surgery using telescopes and specialized instruments, has been shown to be effective for removal of these tumors without needing large ...
The use of chemotherapy to prevent the spread of soft-tissue sarcomas has not been proven to be effective. If the cancer has spread to other areas of the body, chemotherapy may be used to shrink tumors and reduce the pain and discomfort they cause, but is unlikely to eradicate the disease.
Adjuvant chemotherapy is given after surgery to reduce the risk of recurrence. It is used to try to kill any cancer cells that might still exist and cannot be detected through imaging tests. [2] Palliative chemotherapy Palliative chemotherapy is used to control (but not cure) the cancer in settings in which the cancer has spread beyond the ...
Cancer treatments are a wide range of treatments available for the many different types of cancer, with each cancer type needing its own specific treatment. [1] Treatments can include surgery, chemotherapy, radiation therapy, hormonal therapy, targeted therapy including small-molecule drugs or monoclonal antibodies, [2] and PARP inhibitors such as olaparib. [3]
This may be followed by radiotherapy for those at risk of local recurrence or systemic adjuvant medical therapy for those at risk of distant metastasis. Patient with locally advanced invasive breast cancer may be offered neoadjuvant systemic therapy and evaluated for tumor response prior to surgery, radiation, and adjuvant therapy. [31]