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Chemically, PCP is a member of the arylcyclohexylamine class, and pharmacologically, it is a dissociative anesthetic. [4][9][10] PCP works primarily as an NMDA receptor antagonist. [9] PCP is most commonly used in the US. [11] While usage peaked in the US in the 1970s, [12] between 2005 and 2011 an increase in visits to emergency departments as ...
Acepromazine, acetopromazine, or acetylpromazine (commonly known as ACP, Ace, or by the trade names Atravet or Acezine 2, number depending on mg/ml dose) is a phenothiazine derivative antipsychotic drug. It was used in humans during the 1950s as an antipsychotic, [4] but is now almost exclusively used on animals as a sedative and antiemetic.
October 7, 2024 at 1:24 PM. (Reuters) - The U.S. Food and Drug Administration has approved Elanco Animal Health's oral drug to protect dogs against six parasitic infections, the company said on ...
The high affinity of 3-HO-PCP for opioid receptors is unique among arylcyclohexylamines and is in contrast to PCP, which has only very low affinity for the MOR (K i = 11,000–26,000 nM; 282- to 433-fold difference) and the other opioid receptors (K i = 4,100 nM for the KOR and 73,000 nM for the DOR).
Doses as high as 15–20 mg/kg are taken by some recreational users. A single case study suggests that the antidote to dextromethorphan overdose is naloxone, administered intravenously. [17] In addition to producing PCP-like mental effects, high doses may cause a false-positive result for PCP and opiates in some drug tests. [9] [18]
Vet reveals the dog food ingredients you want to feed your pup ... Dog food ingredients explained: A vet's guide to reading a dog food label. Dr Joanna Woodnutt MRCVS. February 9, 2022 at 10:34 AM ...
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