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  2. RNA world - Wikipedia

    en.wikipedia.org/wiki/RNA_world

    The RNA world is a hypothetical stage in the evolutionary history of life on Earth in which self-replicating RNA molecules proliferated before the evolution of DNA and proteins. [1] The term also refers to the hypothesis that posits the existence of this stage. Alexander Rich first proposed the concept of the RNA world in 1962, [2] and Walter ...

  3. Carl Woese - Wikipedia

    en.wikipedia.org/wiki/Carl_Woese

    Carl Richard Woese (/ ˈwoʊz /; [3] July 15, 1928 – December 30, 2012) was an American microbiologist and biophysicist. Woese is famous for defining the Archaea (a new domain of life) in 1977 through a pioneering phylogenetic taxonomy of 16S ribosomal RNA, a technique that has revolutionized microbiology. [4][5][6][7] He also originated the ...

  4. Leslie Orgel - Wikipedia

    en.wikipedia.org/wiki/Leslie_Orgel

    In the late 1960s, Orgel proposed that life was based on RNA before it was based on DNA or proteins. His theory included genes based on RNA and RNA enzymes. [17] This view would be developed and shaped into the now widely accepted RNA world hypothesis. Almost thirty years later, Orgel wrote a lengthy review of the RNA World hypothesis. [18]

  5. Woese's dogma - Wikipedia

    en.wikipedia.org/wiki/Woese's_dogma

    Woese's dogma is a principle of evolutionary biology first put forth by biophysicist Carl Woese in 1977. It states that the evolution of ribosomal RNA was a necessary precursor to the evolution of modern life forms. [1] This led to the advancement of the phylogenetic tree of life consisting of three domains rather than the previously accepted ...

  6. The Major Transitions in Evolution - Wikipedia

    en.wikipedia.org/wiki/The_Major_Transitions_in...

    The Major Transitions in Evolution. The Major Transitions in Evolution is a book written by John Maynard Smith and Eörs Szathmáry (Oxford University Press, 1995). [1][2][3][4] Maynard Smith and Szathmary authored a review article in Nature. [5] Transitions described in the book. Transition from:

  7. Ribozyme - Wikipedia

    en.wikipedia.org/wiki/Ribozyme

    RNA can also act as a hereditary molecule, which encouraged Walter Gilbert to propose that in the distant past, the cell used RNA as both the genetic material and the structural and catalytic molecule rather than dividing these functions between DNA and protein as they are today; this hypothesis is known as the "RNA world hypothesis" of the ...

  8. David Bartel - Wikipedia

    en.wikipedia.org/wiki/David_Bartel

    The HIV rev-RRE interaction (1993) Doctoral advisor. Jack Szostak. David P. Bartel is an American molecular biologist best known for his work on microRNAs. Bartel is a Professor of Biology at the Massachusetts Institute of Technology, Member of the Whitehead Institute, and investigator of the Howard Hughes Medical Institute (HHMI).

  9. John F. Atkins - Wikipedia

    en.wikipedia.org/wiki/John_F._Atkins

    John Atkins is an active proponent of the RNA World hypothesis and is an editor of The RNA World and RNA Worlds books. [10] [11] [12] His research activities include a search for modern protein-free RNA-based life forms. [13] In 2013 John Atkins organized installation of Charles Jencks sculpture ?What is Life? in Irish National Botanic Gardens ...