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Based on a review of this drug by the National Academy of Sciences–National Research Council and/or other information, FDA has classified the indications as follows: "possibly" effective: For use as adjunctive therapy in the treatment of irritable bowel syndrome (irritable colon, spastic colon, mucous colitis) and acute enterocolitis.
Irritable bowel syndrome is a chronic condition that affects the gastrointestinal tract. There is no cure for IBS but many proven treatments. IBS is more common than many realize.
Eluxadoline, sold under the brand names Viberzi and Truberzi, [3] is a medication taken by mouth for the treatment of diarrhea and abdominal pain in individuals with diarrhea-predominant irritable bowel syndrome (IBS-D). [4] It was approved for use in the United States in 2015. [5] The drug originated from Janssen Pharmaceutica and was ...
Dicycloverine is used to treat the symptoms of irritable bowel syndrome, specifically hypermotility, in adults. [ 6 ] [ 7 ] As of 2016, clinical guidelines recommended dicycloverine and other antispasmodics for IBS with diarrhea as a first line treatment.
Historically data from controlled clinical trials have not found a difference from placebo or statistically significant results in the global improvement of IBS. [3] [4] However, more recent systematic reviews found Mebeverine is an effective treatment option in IBS, with a good safety profile and low frequency of adverse effects. [5]
Biotech Lexicon Pharmaceuticals announced Monday that the Food and Drug Administration has given "fast track" status to Lexicon's LX1033 drug to treat diarrhea-predominant irritable bowel syndrome ...
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